Characterization of Nipah Virus from Outbreaks in Bangladesh, 2008–2010

Lo, Michael K.; Lowe, Luis; Hummel, Kimberly B.; Sazzad, Hossain M.S.; Gurley, Emily S.; Hossain, M. Jahangir; Luby, Stephen P.; Miller, David M.; Comer, James A.; Rollin, Pierre E.; Bellini, William J.; Rota, Paul A.

Back to Previous Page

- Add this to...
- Twitter
- Facebook
- Google Bookmarks
- LinkedIn

Characterization of Nipah Virus from Outbreaks in Bangladesh, 2008–2010

Published Date:

Feb 2012

Source:

Emerg Infect Dis. 18(2):248-255.

[PDF-298.55 KB]

Details:

Personal Authors:

Lo, Michael K. ; Lowe, Luis ; Hummel, Kimberly B. ; Sazzad, Hossain M.S. ; Gurley, Emily S. ; ... More ▼

Keywords:

[+]

Description:

Nipah virus (NiV) is a highly pathogenic paramyxovirus that causes fatal encephalitis in humans. The initial outbreak of NiV infection occurred in Malaysia and Singapore in 1998-1999; relatively small, sporadic outbreaks among humans have occurred in Bangladesh since 2001. We characterized the complete genomic sequences of identical NiV isolates from 2 patients in 2008 and partial genomic sequences of throat swab samples from 3 patients in 2010, all from Bangladesh. All sequences from patients in Bangladesh comprised a distinct genetic group. However, the detection of 3 genetically distinct sequences from patients in the districts of Faridpur and Gopalganj indicated multiple co-circulating lineages in a localized region over a short time (January-March 2010). Sequence comparisons between the open reading frames of all available NiV genes led us to propose a standardized protocol for genotyping NiV; this protcol provides a simple and accurate way to classify current and future NiV sequences.

Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases
CDC Public Access

Main Document Checksum:

[+]

Supporting Files:

	license.txt	text/plain
	11-1492-F1.gif	image/gif
	11-1492-F1.jpg	image/jpeg
	11-1492-F2.gif	image/gif
	11-1492-F2.jpg	image/jpeg
	11-1492-Techapp_15p.pdf	application/pdf
	11-1492_finalR.nxml	text/plain

No Related Documents.

You May Also Like:

Nipah Virus Infection Outbreak with Nosocomial and Corpse-to-Human Transmission, Bangladesh

Personal Author:

Sazzad, Hossain M.S.; Hossain, M. Jahangir; Gurley, Emily S.; Ameen, Kazi M.H.; Parveen, Shahana; Islam, M. Saiful; Faruque, Labib I.; Podder, Goutam; Banu, Sultana S.; Lo, Michael K.; Rollin, Pierre E.; Rota, Paul A.; Daszak, Peter; Rahman, Mahmudur; Luby, Stephen P.;

Published:

Feb 2013

Source:

Emerg Infect Dis. 19(2):210-217.

Description:

Active Nipah virus encephalitis surveillance identified an encephalitis cluster and sporadic cases in Faridpur, Bangladesh, in January 2010. We identified 16 case-patients; 14 of these patients died. For 1 case-patient, the only known exposure was hu...

File Type:

[PDF - 881.25 KB]
Isolation and Full-Genome Characterization of Nipah Viruses from Bats, Bangladesh

Personal Author:

Anderson, Danielle E.; Islam, Ariful; Crameri, Gary; Todd, Shawn; Islam, Ausraful; Khan, Salah U.; Foord, Adam; Rahman, Mohammed Z.; Mendenhall, Ian H.; Luby, Stephen P.; Gurley, Emily S.; Daszak, Peter; Epstein, Jonathan H.; Wang, Lin-Fa;

Published:

January 2019

Source:

Emerg Infect Dis. 25(1):166-170

Description:

Despite molecular and serologic evidence of Nipah virus in bats from various locations, attempts to isolate live virus have been largely unsuccessful. We report isolation and full-genome characterization of 10 Nipah virus isolates from Pteropus mediu...

File Type:

[PDF - 1.38 MB]
Evolving epidemiology of Nipah virus infection in Bangladesh: evidence from outbreaks during 2010–2011

Personal Author:

CHAKRABORTY, A.; SAZZAD, H. M. S.; HOSSAIN, M. J.; ISLAM, M. S.; PARVEEN, S.; HUSAIN, M.; BANU, S. S.; PODDER, G.; AFROJ, S.; ROLLIN, P. E.; DASZAK, P.; LUBY, S. P.; RAHMAN, M.; GURLEY, E. S.;

Published:

Jun 30 2015

Source:

Epidemiol Infect. 144(2):371-380.

Description:

Drinking raw date palm sap is the primary route of Nipah virus (NiV) transmission from bats to people in Bangladesh; subsequent person-to-person transmission is common. During December 2010 to March 2011, we investigated NiV epidemiology by interview...

File Type:

[PDF - 356.58 KB]
Nipah Virus Sequences from Humans and Bats during Nipah Outbreak, Kerala, India, 2018

Personal Author:

Yadav, Pragya D.; Shete, Anita M.; Kumar, G. Arun; Sarkale, Prasad; Sahay, Rima R.; Radhakrishnan, Chandni; Lakra, Rajen; Pardeshi, Prachi; Gupta, Nivedita; Gangakhedkar, Raman R.; Rajendran, V.R.; Sadanandan, Rajeev; Mourya, Devendra T.;

Published:

May 2019

Source:

Emerg Infect Dis. 25(5):1003-1006

Description:

We retrieved Nipah virus (NiV) sequences from 4 human and 3 fruit bat (Pteropus medius) samples from a 2018 outbreak in Kerala, India. Phylogenetic analysis demonstrated that NiV from humans was 96.15% similar to a Bangladesh strain but 99.7%-100% si...

File Type:

[PDF - 1.40 MB]
Nipah Virus Contamination of Hospital Surfaces during Outbreaks, Bangladesh, 2013–2014

Personal Author:

Hassan, Md Zakiul; Sazzad, Hossain M.S.; Luby, Stephen P.; Sturm-Ramirez, Katharine; Bhuiyan, Mejbah Uddin; Rahman, Mohammed Ziaur; Islam, Md Muzahidul; Ströher, Ute; Sultana, Sharmin; Kafi, Mohammad Abdullah Heel; Daszak, Peter; Rahman, Mahmudur; Gurley, Emily S.;

Published:

Jan 2018

Source:

Emerg Infect Dis. 24(1):15-21.

Description:

Nipah virus (NiV) has been transmitted from patient to caregivers in Bangladesh presumably through oral secretions. We aimed to detect whether NiV-infected patients contaminate hospital surfaces with the virus. During December 2013-April 2014, we col...

File Type:

[PDF - 595.59 KB]