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Cost-effectiveness of breast cancer screening in the National Breast and Cervical Cancer Early Detection Program
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8 2019
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Source: Cancer Causes Control. 30(8):819-826
[PDF-228.09 KB]
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Alternative Title:Cancer Causes Control
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Description:Purpose
To estimate the cost-effectiveness of breast cancer screening in the National Breast and Cervical Cancer Early Detection Program (NBCCEDP).
Methods
Using a modified CISNET breast cancer simulation model, we estimated outcomes for women aged 40–64 years associated with three scenarios: breast cancer screening within the NBCCEDP, screening in the absence of the NBCCEDP (no program), and no screening through any program. We report screening outcomes, cost, quality-adjusted life-years (QALYs), incremental cost-effectiveness ratios (ICERs), and sensitivity analyses results.
Results
Compared with no program and no screening, the NBCCEDP lowers breast cancer mortality and improves QALYs, but raises health care costs. Base-case ICER for the program was $51,754/QALY versus no program and $50,223/QALY versus no screening. Probabilistic sensitivity analysis ICER for the program was $56,615/QALY [95% CI $24,069, $134,230/QALY] versus no program and $51,096/QALY gained [95% CI $26,423, $97,315/QALY] versus no screening.
Conclusions
On average, breast cancer screening in the NBCCEDP was cost-effective compared with no program or no screening.
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Pubmed ID:31098856
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Pubmed Central ID:PMC6613985
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