Details:

Alternative Title:
Cancer Causes Control
Personal Author:
Rim, Sun Hee ; Allaire, Benjamin T. ; Ekwueme, Donatus U. ; Miller, Jacqueline W. ; Subramanian, Sujha ; ... More +
Rim, Sun Hee ; Allaire, Benjamin T. ; Ekwueme, Donatus U. ; Miller, Jacqueline W. ; Subramanian, Sujha ; Hall, Ingrid J. ; Hoerger, Thomas J. Less -
Description:
Purpose

To estimate the cost-effectiveness of breast cancer screening in the National Breast and Cervical Cancer Early Detection Program (NBCCEDP).

Methods

Using a modified CISNET breast cancer simulation model, we estimated outcomes for women aged 40–64 years associated with three scenarios: breast cancer screening within the NBCCEDP, screening in the absence of the NBCCEDP (no program), and no screening through any program. We report screening outcomes, cost, quality-adjusted life-years (QALYs), incremental cost-effectiveness ratios (ICERs), and sensitivity analyses results.

Results

Compared with no program and no screening, the NBCCEDP lowers breast cancer mortality and improves QALYs, but raises health care costs. Base-case ICER for the program was $51,754/QALY versus no program and $50,223/QALY versus no screening. Probabilistic sensitivity analysis ICER for the program was $56,615/QALY [95% CI $24,069, $134,230/QALY] versus no program and $51,096/QALY gained [95% CI $26,423, $97,315/QALY] versus no screening.

Conclusions

On average, breast cancer screening in the NBCCEDP was cost-effective compared with no program or no screening.


Subject:
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Adult
Article
Breast Neoplasms
Cost-Benefit Analysis
Early Detection Of Cancer
Female
Humans
Mass Screening
Middle Aged
National Health Programs
Quality-Adjusted Life Years

Source:
Cancer Causes Control. 30(8):819-826
Pubmed ID:
31098856
Pubmed Central ID:
PMC6613985
Document Type:
Journal Article
Funding:
CC999999/Intramural CDC HHS/United States ; This research was supported by Contract No. 200-2008-27958 from the Centers for Disease Control and Prevention/Centers for Disease Control and Prevention/
CC999999/Intramural CDC HHS/United States ; This research was supported by Contract No. 200-2008-27958 from the Centers for Disease Control and Prevention/Centers for Disease Control and Prevention/ Less -
Name as Subject:
National Breast and Cervical Cancer Early Detection Program (U.S.)
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:b96da48c721b65812aa5a617d8a768c1459d6428077c28c1c290044088521809
File Type:

Supporting Files

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  	NIHMS1037578-supplement-Appendix.docx	docx

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