Cost-effectiveness of breast cancer screening in the National Breast and Cervical Cancer Early Detection Program

Details

• Alternative Title:
  Cancer Causes Control
• Personal Author:
  Rim, Sun Hee ; Allaire, Benjamin T. ; Ekwueme, Donatus U. ; Miller, Jacqueline W. ; Subramanian, Sujha ; Hall, Ingrid J. ; Hoerger, Thomas J.
• Description:
  Purpose
  
  To estimate the cost-effectiveness of breast cancer screening in the National Breast and Cervical Cancer Early Detection Program (NBCCEDP).
  
  Methods
  
  Using a modified CISNET breast cancer simulation model, we estimated outcomes for women aged 40–64 years associated with three scenarios: breast cancer screening within the NBCCEDP, screening in the absence of the NBCCEDP (no program), and no screening through any program. We report screening outcomes, cost, quality-adjusted life-years (QALYs), incremental cost-effectiveness ratios (ICERs), and sensitivity analyses results.
  
  Results
  
  Compared with no program and no screening, the NBCCEDP lowers breast cancer mortality and improves QALYs, but raises health care costs. Base-case ICER for the program was $51,754/QALY versus no program and $50,223/QALY versus no screening. Probabilistic sensitivity analysis ICER for the program was $56,615/QALY [95% CI $24,069, $134,230/QALY] versus no program and $51,096/QALY gained [95% CI $26,423, $97,315/QALY] versus no screening.
  
  Conclusions
  
  On average, breast cancer screening in the NBCCEDP was cost-effective compared with no program or no screening.
  
  
• Subjects:
  Adult Breast Neoplasms Cost-Benefit Analysis Early Detection Of Cancer Female Humans Mass Screening Middle Aged National Health Programs Quality-Adjusted Life Years
• Keywords:
  Breast Cancer Cost-effectiveness Economic Analysis NBCCEDP Screening
• Source:
  Cancer Causes Control. 30(8):819-826
• Pubmed ID:
  31098856
• Pubmed Central ID:
  PMC6613985
• Document Type:
  Journal Article
• Funding:
  CC999999/Intramural CDC HHSUnited States/ ; This research was supported by Contract No. 200-2008-27958 from the Centers for Disease Control and Prevention/Centers for Disease Control and Prevention/
• Volume:
  30
• Issue:
  8
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:6f0cc39e6aec503cb1321270d3c18329131a6c10b6bd69261f529304070a90a62b2699bd84685654ba1957edc2a25a9a533a0d066bdb642843408508da2826cf
• Download URL:
  https://stacks.cdc.gov/view/cdc/79708/cdc_79708_DS1.pdf
• File Type:
  [PDF - 228.09 KB ]