Candida auris, Colombia, 2016

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Armstrong, Paige A. ; Rivera, Sandra M. ; Escandon, Patricia ; Caceres, Diego H. ; Chow, Nancy ; Stuckey, Matthew J. ; Díaz, Jorge ; Gomez, Adriana ; Vélez, Norida ; Espinosa-Bode, Andres ; Salcedo, Soraya ; Marin, Adriana ; Berrio, Indira ; Varón, Carmen ; Guzman, Angel ; Pérez-Franco, Jairo E. ; Escobar, Julian D. ; Villalobos, Nohora ; Correa, Juan M. ; Litvintseva, Anastasia P. ; Lockhart, Shawn R. ; Fagan, Ryan ; Chiller, Tom M. ; Jackson, Brendan ; Pacheco, Oscar
• Description:
  Candida auris is an emerging multidrug-resistant fungus that causes hospital-associated outbreaks of invasive infections with high death rates. During 2015-2016, health authorities in Colombia detected an outbreak of C. auris. We conducted an investigation to characterize the epidemiology, transmission mechanisms, and reservoirs of this organism. We investigated 4 hospitals with confirmed cases of C. auris candidemia in 3 cities in Colombia. We abstracted medical records and collected swabs from contemporaneously hospitalized patients to assess for skin colonization. We identified 40 cases; median patient age was 23 years (IQR 4 months-56 years). Twelve (30%) patients were <1 year of age, and 24 (60%) were male. The 30-day mortality was 43%. Cases clustered in time and location; axilla and groin were the most commonly colonized sites. Temporal and spatial clustering of cases and skin colonization suggest person-to-person transmission of C. auris. These cases highlight the importance of adherence to infection control recommendations.
• Subjects:
  Antimicrobial Resistance Candida Auris Candidemia Colombia Fungi Healthcare-Associated Hospital-Associated Multicenter Outbreak Of Emerging Fungus Candida Auris, Colombia, 2016 Nosocomial Infections Research
• Source:
  Emerg Infect Dis. 25(7):1339-1346
• Pubmed ID:
  31211679
• Pubmed Central ID:
  PMC6590770
• Document Type:
  Journal Article
• Volume:
  25
• Issue:
  7
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:53a8b0618adc1d5e76deb759f5be1eaae79eb1374478c0acf9e6b54b2a5f37bf
• Download URL:
  https://stacks.cdc.gov/view/cdc/79607/cdc_79607_DS1.pdf
• File Type:
  [PDF - 949.34 KB ]