Health Benefits, Risks, and Cost-Effectiveness of Influenza Vaccination of Children

Prosser, Lisa A.; Bridges, Carolyn Buxton; Uyeki, Timothy M.; Hinrichsen, Virginia L.; Meltzer, Martin I.; Molinari, Noelle-Angelique M.; Schwartz, Benjamin; Thompson, William W.; Fukuda, Keiji; Lieu, Tracy A.

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Health Benefits, Risks, and Cost-Effectiveness of Influenza Vaccination of Children

Published Date:

Oct 2006

Source:

Emerg Infect Dis. 12(10):1548-1558.

Language:

English

[PDF-461.07 KB]

Details:

Alternative Title:

Emerg Infect Dis

Personal Author:

Prosser, Lisa A. ; Bridges, Carolyn Buxton ; Uyeki, Timothy M. ; Hinrichsen, Virginia L. ; Meltzer, Martin I. ; ... More ▼

Description:

We estimated cost-effectiveness of annually vaccinating children not at high risk with inactivated influenza vaccine (IIV) to range from US $12,000 per quality-adjusted life year (QALY) saved for children ages 6-23 months to $119,000 per QALY saved for children ages 12-17 years. For children at high risk (preexisting medical conditions) ages 6-35 months, vaccination with IIV was cost saving. For children at high risk ages 3-17 years, vaccination cost $1,000-$10,000 per QALY. Among children notat high risk ages 5-17 years, live, attenuated influenza vaccine had a similar cost-effectiveness as IIV. Risk status was more important than age in determining the economic effects of annual vaccination, and vaccination was less cost-effective as the child's age increased. Thus, routine vaccination of all children is likely less cost-effective than vaccination of all children ages 6-23 months plus all other children at high risk.

Subject:

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Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases

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Health Benefits, Risks, and Cost-Effectiveness of Influenza Vaccination of Children

Health Benefits, Risks, and Cost-Effectiveness of Influenza Vaccination of Children

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