Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Prosser, Lisa A. ; Bridges, Carolyn Buxton ; Uyeki, Timothy M. ; Hinrichsen, Virginia L. ; Meltzer, Martin I. ; ... More +
Prosser, Lisa A. ; Bridges, Carolyn Buxton ; Uyeki, Timothy M. ; Hinrichsen, Virginia L. ; Meltzer, Martin I. ; Molinari, Noelle-Angelique M. ; Schwartz, Benjamin ; Thompson, William W. ; Fukuda, Keiji ; Lieu, Tracy A. Less -
Description:
We estimated cost-effectiveness of annually vaccinating children not at high risk with inactivated influenza vaccine (IIV) to range from US $12,000 per quality-adjusted life year (QALY) saved for children ages 6-23 months to $119,000 per QALY saved for children ages 12-17 years. For children at high risk (preexisting medical conditions) ages 6-35 months, vaccination with IIV was cost saving. For children at high risk ages 3-17 years, vaccination cost $1,000-$10,000 per QALY. Among children notat high risk ages 5-17 years, live, attenuated influenza vaccine had a similar cost-effectiveness as IIV. Risk status was more important than age in determining the economic effects of annual vaccination, and vaccination was less cost-effective as the child's age increased. Thus, routine vaccination of all children is likely less cost-effective than vaccination of all children ages 6-23 months plus all other children at high risk.
Subject:
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Adolescent
Child
Child, Preschool
Cost-Benefit Analysis
Humans
Infant
Influenza Vaccines
Mass Vaccination
Quality Of Life
Research
Sensitivity And Specificity
Vaccines, Inactivated

Source:
Emerg Infect Dis. 12(10):1548-1558.
Document Type:
Journal Article
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
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urn:sha256:d557978e2a303825e99951d21f312fa00d35f958c1ad13cd29ac98bd0d97c7e5
File Type:

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