Chronic Q Fever Diagnosis—Consensus Guideline versus Expert Opinion

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Kampschreur, Linda M. ; Wegdam-Blans, Marjolijn C.A. ; Wever, Peter C. ; Renders, Nicole H.M. ; Delsing, Corine E. ; Sprong, Tom ; van Kasteren, Marjo E.E. ; Bijlmer, Henk ; Notermans, Daan ; Oosterheert, Jan Jelrik ; Stals, Frans S. ; Nabuurs-Franssen, Marrigje H. ; Bleeker-Rovers, Chantal P.
• Corporate Authors:
  on behalf of the Dutch Q Fever Consensus Group
• Description:
  Chronic Q fever, caused by Coxiella burnetii, has high mortality and morbidity rates if left untreated. Controversy about the diagnosis of this complex disease has emerged recently. We applied the guideline from the Dutch Q Fever Consensus Group and a set of diagnostic criteria proposed by Didier Raoult to all 284 chronic Q fever patients included in the Dutch National Chronic Q Fever Database during 2006–2012. Of the patients who had proven cases of chronic Q fever by the Dutch guideline, 46 (30.5%)would not have received a diagnosis by the alternative criteria designed by Raoult, and 14 (4.9%) would have been considered to have possible chronic Q fever. Six patients with proven chronic Q fever died of related causes. Until results from future studies are available, by which current guidelines can be modified, we believe that the Dutch literature-based consensus guideline is more sensitive and easier to use in clinical practice.
• Subjects:
  Expert Testimony Humans Practice Guidelines As Topic Q Fever
• Source:
  Emerg Infect Dis. 21(7):1183-1188
• Pubmed ID:
  26277798
• Pubmed Central ID:
  PMC4480373
• Document Type:
  Journal Article
• Place as Subject:
  Netherlands
• Volume:
  21
• Issue:
  7
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:ad2809f23190e924c83f231a8ab04400117ae2f7d7c948a89d4229f2acbc02bc
• Download URL:
  https://stacks.cdc.gov/view/cdc/77274/cdc_77274_DS1.pdf
• File Type:
  [PDF - 1.17 MB ]