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Chikungunya Virus Control: Is a Vaccine on the Horizon?
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  1. Differential Shedding and Antibody Kinetics of Zika and Chikungunya Viruses, Brazil
    Personal Author:
    Bozza, Fernando A.; Moreira-Soto, Andres; Rockstroh, Alexandra; Fischer, Carlo; Nascimento, Alessandra D.; Calheiros, Andrea S.; Drosten, Christian; Bozza, Patrícia T.; Souza, Thiago Moreno L.; Ulbert, Sebastian; Drexler, Jan Felix;
    Published Date:
    Feb 2019
    Source:
    Emerg Infect Dis. 25(2):311-315
    Description:
    In seroconversion panels obtained from patients from Brazil, diagnostic testing for Zika virus infection was improved by combining multiple antibody isotypes, techniques, and antigens, but sensitivity remained suboptimal. In contrast, chikungunya vir...
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    Navarro-Torné, Adoración; Hanrahan, Finnian; Kerstiëns, Barbara; Aguar, Pilar; Matthiessen, Line;
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    Influenza virus infections are a major public health threat. Vaccination is available, but unpredictable antigenic changes in circulating strains require annual modification of seasonal influenza vaccines. Vaccine effectiveness has proven limited, pa...
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    Van Gompel, Alfons; Van Bortel, Wim;
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  4. Basic Reproduction Number of Chikungunya Virus Transmitted by Aedes Mosquitoes
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    Haider, Najmul; Vairo, Francesco; Ippolito, Giuseppe; Zumla, Alimuddin; Kock, Richard A.;
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    Emerg Infect Dis. 26(10):2429-2431
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    We estimated the weighted mean basic reproduction number (R|) of chikungunya virus based on outbreak size. R| was 3.4 (95% CI 2.4-4.2) and varied for 2 primary chikungunya mosquito vectors: 4.1 (95% CI 1.5-6.6) for Aedes aegypti and 2.8 (95% CI 1.8-3...
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  5. Zika Virus Persistence and Higher Viral Loads in Cutaneous Capillaries Than in Venous Blood
    Personal Author:
    Matheus, Séverine; de Laval, Franck; Moua, David; N’Guyen, Christophe; Martinez, Enguerrane; Rousset, Dominique; Briolant, Sébastien;
    Published Date:
    Nov 17 2017
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    Emerg Infect Dis. 23(11):1910-1911.
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    We collected venous and capillary serum samples from 21 Zika virus‒infected patients on multiple days after symptom onset and found RNA load was higher and median duration of virus detection significantly longer in capillary than in venous blood. T...
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