Differential Shedding and Antibody Kinetics of Zika and Chikungunya Viruses, Brazil

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Bozza, Fernando A. ; Moreira-Soto, Andres ; Rockstroh, Alexandra ; Fischer, Carlo ; Nascimento, Alessandra D. ; Calheiros, Andrea S. ; Drosten, Christian ; Bozza, Patrícia T. ; Souza, Thiago Moreno L. ; Ulbert, Sebastian ; Drexler, Jan Felix
• Description:
  In seroconversion panels obtained from patients from Brazil, diagnostic testing for Zika virus infection was improved by combining multiple antibody isotypes, techniques, and antigens, but sensitivity remained suboptimal. In contrast, chikungunya virus diagnostic testing was unambiguous. Recurrent recent arbovirus infections suggested by serologic data and unspecific symptoms highlight the need for exhaustive virologic testing.
• Subjects:
  Adult Antibodies, Viral Chikungunya Fever Chikungunya Virus Female Humans Immunoassay Male Virus Shedding Zika Virus Zika Virus Infection

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• Source:
  Emerg Infect Dis. 25(2):311-315
• Document Type:
  Journal Article
• Genre:
  Dispatch
• Place as Subject:
  Brazil
• Volume:
  25
• Issue:
  2
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha-512:a955aa5b1c55e51eb6e510850354e121d7fd8e0e339d2d6e8f0e6a99c54cc94113011eb12e0a68c81d76b7997325522f2c6b5e677fc29f10135133c18ee1d8a6
• Download URL:
  https://stacks.cdc.gov/view/cdc/76783/cdc_76783_DS1.pdf
• File Type:
  [PDF - 1.67 MB ]