Tick-Borne Relapsing Fever in the White Mountains, Arizona, USA, 2013–2018

Mafi, Neema; Yaglom, Hayley D.; Levy, Craig; Taylor, Anissa; O’Grady, Catherine; Venkat, Heather; Komatsu, Kenneth K.; Roller, Brentin; Seville, Maria T.; Kusne, Shimon; Po, John Leander; Thorn, Shannon; Ampel, Neil M.

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Tick-Borne Relapsing Fever in the White Mountains, Arizona, USA, 2013–2018

Supporting Files Public Domain

Apr 2019
By Mafi, Neema ; Yaglom, Hayley D. ; Levy, Craig ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Mafi, Neema ; Yaglom, Hayley D. ; Levy, Craig ; Taylor, Anissa ; O’Grady, Catherine ; Venkat, Heather ; Komatsu, Kenneth K. ; Roller, Brentin ; Seville, Maria T. ; Kusne, Shimon ; Po, John Leander ; Thorn, Shannon ; Ampel, Neil M.
Description:

Tick-borne relapsing fever (TBRF) is a bacterial infection transmitted by tick bites that occurs in several different parts of the world, including the western United States. We describe 6 cases of TBRF acquired in the White Mountains of Arizona, USA, and diagnosed during 2013-2018. All but 1 case-patient had recurrent fever, and some had marked laboratory abnormalities, including leukopenia, thrombocytopenia, hyperbilirubinemia, and elevated aminotransaminases. One patient had uveitis. Diagnosis was delayed in 5 of the cases; all case-patients responded to therapy with doxycycline. Two patients had Jarisch-Herxheimer reactions. The White Mountains of Arizona have not been previously considered a region of high incidence for TBRF. These 6 cases likely represent a larger number of cases that might have been undiagnosed. Clinicians should be aware of TBRF in patients who reside, recreate, or travel to this area and especially for those who sleep overnight in cabins there.
Subjects:

Bacteria Bacterial Infections Borrelia Hermsii Public Health Relapsing Fever Synopsis TBRF Tick-borne Relapsing Fever Tickborne Diseases Ticks Vector-borne Infections White Mountains Zoonoses
Source:

Emerg Infect Dis. 25(4):649-653
Pubmed ID:

30882304
Pubmed Central ID:

PMC6433026
Document Type:

Journal Article
Place as Subject:

Arizona
Location:

North America
Volume:

25
Issue:

4
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:8c69fbca8602e4a99ecde68ed501e30dad41a041b79003d43a627c295ca75b3c
Download URL:

https://stacks.cdc.gov/view/cdc/77150/cdc_77150_DS1.pdf
File Type:

[PDF - 1.11 MB ]

File Language:

English

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