Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Trung, Nguyen Vu ; Hoi, Le Thi ; Dien, Vu Minh ; Huong, Dang Thi ; Hoa, Tran Mai ; ... More +
Trung, Nguyen Vu ; Hoi, Le Thi ; Dien, Vu Minh ; Huong, Dang Thi ; Hoa, Tran Mai ; Lien, Vu Ngoc ; Van Luan, Phan ; Lewycka, Sonia Odette ; Choisy, Marc ; Bryant, Juliet E. ; Nadjm, Behzad ; Rogier van Doorn, H. ; Richards, Allen L. ; Van Kinh, Nguyen Less -
Description:
Rickettsioses are endemic to Vietnam; however, only a limited number of clinical studies have been performed on these vectorborne bacteria. We conducted a prospective hospital-based study at 2 national referral hospitals in Hanoi to describe the clinical characteristics of scrub typhus and murine typhus in northern Vietnam and to assess the diagnostic applicability of quantitative real-time PCR assays to diagnose rickettsial diseases. We enrolled 302 patients with acute undifferentiated fever and clinically suspected rickettsiosis during March 2015-March 2017. We used a standardized case report form to collect clinical information and laboratory results at the time of admission and during treatment. We confirmed scrub typhus in 103 (34.1%) patients and murine typhus in 12 (3.3%) patients. These results highlight the need for increased emphasis on training for healthcare providers for earlier recognition, prevention, and treatment of rickettsial diseases in Vietnam.
Subject:
[+]
Adult
Early Diagnosis
Female
Humans
Male
Middle Aged
Pathology, Molecular
Prospective Studies
Scrub Typhus
Serotyping
Typhus, Endemic Flea-Borne

Source:
Emerg Infect Dis. 25(4):633-641
Pubmed ID:
30882318
Pubmed Central ID:
PMC6433017
Document Type:
Journal Article
Place as Subject:
Vietnam
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:70f571408d4dcd62e82ed465191534685d2d94d5fb2e152da16156a0fa548f47
File Type:

Supporting Files

• 	18-0691-F1.gif	gif
  	18-0691-F1.jpg	jpeg
  	18-0691-F2.gif	gif
  	18-0691-F2.jpg	jpeg
  	18-0691-F3.gif	gif
  	18-0691-F3.jpg	jpeg
  	18-0691-Techapp-s1.pdf	pdf
  	18-0691.nxml	xml

More +