Mucosal Leishmaniasis in Travelers with Leishmania braziliensis Complex Returning to Israel

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Solomon, Michal ; Sahar, Nadav ; Pavlotzky, Felix ; Barzilai, Aviv ; Jaffe, Charles L. ; Nasereddin, Abedelmajeed ; Schwartz, Eli
• Description:
  Mucosal leishmaniasis (ML) is a complication of New World cutaneous leishmaniasis (CL) caused mainly by Leishmania (Viannia) braziliensis. This retrospective study investigated all cases of ML caused by L. (V.) braziliensis in a tertiary medical center in Israel, evaluating the risk factors, clinical presentations, diagnosis, treatment, and outcome of mucosal involvement in ML caused by L. (V.) braziliensis in travelers returning to Israel. During 1993-2015, a total of 145 New World CL cases were seen in travelers returning from Bolivia; among them, 17 (11.7%) developed ML. Nasopharyngeal symptoms developed 0-3 years (median 8 months) after exposure. The only significant risk factor for developing ML was the absence of previous systemic treatment. Among untreated patients, 41% developed ML, compared with only 3% of treated patients (p = 0.005). Systemic treatment for CL seems to be a protective factor against developing ML.
• Subjects:
  Adult Communicable Diseases, Imported Diagnosis, Differential Female Humans Leishmania Braziliensis Leishmaniasis, Mucocutaneous Male Pathology, Molecular Retrospective Studies Risk Factors Skin Diseases, Parasitic Travel-Related Illness

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• Source:
  Emerg Infect Dis. 25(4):642-648
• Pubmed ID:
  30882319
• Pubmed Central ID:
  PMC6433024
• Document Type:
  Journal Article
• Genre:
  Synopsis
• Place as Subject:
  Bolivia ; Israel
• Volume:
  25
• Issue:
  4
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:01ab7d04ea5b2e815c3fde136d44ef0d01260aeeb7766dced18a9fefcb623377
• Download URL:
  https://stacks.cdc.gov/view/cdc/77129/cdc_77129_DS1.pdf
• File Type:
  [PDF - 1.11 MB ]