Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Peña, Farah ; Pimentel, Raquel ; Khosla, Shaveta ; Mehta, Supriya D. ; Brito, Maximo O.
Peña, Farah ; Pimentel, Raquel ; Khosla, Shaveta ; Mehta, Supriya D. ; Brito, Maximo O. Less -
Description:
Zika virus infection during pregnancy may result in birth defects and pregnancy complications. We describe the Zika virus outbreak in pregnant women in the Dominican Republic during 2016-2017. We conducted multinomial logistic regression to identify factors associated with fetal losses and preterm birth. The Ministry of Health identified 1,282 pregnant women with suspected Zika virus infection, a substantial proportion during their first trimester. Fetal loss was reported for ≈10% of the reported pregnancies, and 3 cases of fetal microcephaly were reported. Women infected during the first trimester were more likely to have early fetal loss (adjusted odds ratio 5.9, 95% CI 3.5-10.0). Experiencing fever during infection was associated with increased odds of premature birth (adjusted odds ratio 1.65, 95% CI 1.03-2.65). There was widespread morbidity during the epidemic. Our findings strengthen the evidence for a broad range of adverse pregnancy outcomes resulting from Zika virus infection.
Subjects:
[+]
Adolescent Adult Child Cross-Sectional Studies Disease Outbreaks Epidemics Female History, 21St Century Humans Pregnancy Pregnancy Complications, Infectious/Epidemiology Pregnancy Complications, Infectious/History Pregnancy Complications, Infectious/Virology Pregnancy Outcome Public Health Surveillance Risk Factors Young Adult Zika Virus Zika Virus Infection/Diagnosis Zika Virus Infection/Epidemiology Zika Virus Infection/History Zika Virus Infection/Virology
Source:
Emerg Infect Dis. 25(2):247-255
Pubmed ID:
30666928
Pubmed Central ID:
PMC6346438
Document Type:
Journal Article
Genre:
Historical Article
Place as Subject:
Dominican Republic
Location:
Caribbean
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:bad474fa1b6097d4253cee8e2e1a496388dec1443ae158a17cb1a0368677832b
Download URL:
https://stacks.cdc.gov/view/cdc/76797/cdc_76797_DS1.pdf
File Type:

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