Echinococcus multilocularis Infection, Southern Ontario, Canada

Kotwa, Jonathon D.; Isaksson, Mats; Jardine, Claire M.; Campbell, G. Douglas; Berke, Olaf; Pearl, David L.; Mercer, Nicola J.; Osterman-Lind, Eva; Peregrine, Andrew S.

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Echinococcus multilocularis Infection, Southern Ontario, Canada

Supporting Files

Feb 2019
By Kotwa, Jonathon D. ; Isaksson, Mats ; Jardine, Claire M. ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Kotwa, Jonathon D. ; Isaksson, Mats ; Jardine, Claire M. ; Campbell, G. Douglas ; Berke, Olaf ; Pearl, David L. ; Mercer, Nicola J. ; Osterman-Lind, Eva ; Peregrine, Andrew S.
Description:

Alveolar echinococcosis, the disease caused by infection with the intermediate stage of the Echinococcus multilocularis tapeworm, is typically fatal in humans and dogs when left untreated. Since 2012, alveolar echinococcosis has been diagnosed in 5 dogs, 3 lemurs, and 1 chipmunk in southern Ontario, Canada, a region previously considered free of these tapeworms. Because of human and animal health concerns, we estimated prevalence of infection in wild canids across southern Ontario. During 2015-2017, we collected fecal samples from 460 wild canids (416 coyotes, 44 foxes) during postmortem examination and analyzed them by using a semiautomated magnetic capture probe DNA extraction and real-time PCR method for E. multilocularis DNA. Surprisingly, 23% (95% CI 20%-27%) of samples tested positive. By using a spatial scan test, we identified an infection cluster (relative risk 2.26; p = 0.002) in the western-central region of the province. The cluster encompasses areas of dense human population, suggesting zoonotic transmission.
Subjects:

Alveolar Echinococcosis Canis Latrans Cestodes Coyotes Distribution Dogs Echinococcus Multilocularis Foxes Parasites Prevalence Public Health Research Vulpes Vulpes Wild Canids Zoonoses
Source:

Emerg Infect Dis. 25(2):265-272
Pubmed ID:

30666935
Pubmed Central ID:

PMC6346450
Document Type:

Journal Article
Funding:

Wellcome Trust/United Kingdom
Place as Subject:

Ontario, Canada
Location:

North America
Volume:

25
Issue:

2
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:8cedc4dee91b10abbca8c9a39797dab3cb2535edb856276f37d2f600ce11a24d
Download URL:

https://stacks.cdc.gov/view/cdc/76787/cdc_76787_DS1.pdf
File Type:

[PDF - 1.48 MB ]

File Language:

English

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