Trends of Human Plague, Madagascar, 1998–2016

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Andrianaivoarimanana, Voahangy ; Piola, Patrice ; Wagner, David M. ; Rakotomanana, Fanjasoa ; Maheriniaina, Viviane ; Andrianalimanana, Samuel ; Chanteau, Suzanne ; Rahalison, Lila ; Ratsitorahina, Maherisoa ; Rajerison, Minoarisoa
• Description:
  Madagascar is more seriously affected by plague, a zoonosis caused by Yersinia pestis, than any other country. The Plague National Control Program was established in 1993 and includes human surveillance. During 1998-2016, a total of 13,234 suspected cases were recorded, mainly from the central highlands; 27% were confirmed cases, and 17% were presumptive cases. Patients with bubonic plague (median age 13 years) represented 93% of confirmed and presumptive cases, and patients with pneumonic plague (median age 29 years) represented 7%. Deaths were associated with delay of consultation, pneumonic form, contact with other cases, occurrence after 2009, and not reporting dead rats. A seasonal pattern was observed with recrudescence during September-March. Annual cases peaked in 2004 and decreased to the lowest incidence in 2016. This overall reduction occurred primarily for suspected cases and might be caused by improved adherence to case criteria during widespread implementation of the F1 rapid diagnostic test in 2002.
• Subjects:
  Antigens, Bacterial Case-Control Studies Data Analysis Disease Outbreaks History, 20th Century History, 21st Century Humans Immunoassay Plague/diagnosis Plague/epidemiology Plague/history Plague/microbiology Population Surveillance Risk Factors Seroepidemiologic Studies Synopsis Yersinia Pestis

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• Source:
  Emerg Infect Dis. 25(2):220-228
• Pubmed ID:
  30666930
• Pubmed Central ID:
  PMC6346457
• Document Type:
  Journal Article
• Place as Subject:
  Madagascar
• Location:
  Africa
• Volume:
  25
• Issue:
  2
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:d4d7aefa520d2d26087178ca95767365f7c506ad917cd3be383c031b767e0e15
• Download URL:
  https://stacks.cdc.gov/view/cdc/76779/cdc_76779_DS1.pdf
• File Type:
  [PDF - 1.19 MB ]