University-Based Outbreaks of Meningococcal Disease Caused by Serogroup B, United States, 2013–2018

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Soeters, Heidi M. ; McNamara, Lucy A. ; Blain, Amy E. ; Whaley, Melissa ; MacNeil, Jessica R. ; Hariri, Susan ; Mbaeyi, Sarah A.
• Corporate Authors:
  for the Serogroup B Meningococcal Disease University Outbreak Group
• Description:
  We reviewed university-based outbreaks of meningococcal disease caused by serogroup B and vaccination responses in the United States in the years following serogroup B meningococcal (MenB) vaccine availability. Ten university-based outbreaks occurred in 7 states during 2013-2018, causing a total of 39 cases and 2 deaths. Outbreaks occurred at universities with 3,600-35,000 undergraduates. Outbreak case counts ranged from 2 to 9 cases; outbreak duration ranged from 0 to 376 days. All 10 universities implemented MenB vaccination: 3 primarily used MenB-FHbp and 7 used MenB-4C. Estimated first-dose vaccination coverage ranged from 14% to 98%. In 5 outbreaks, additional cases occurred 6-259 days following MenB vaccination initiation. Although it is difficult to predict outbreak trajectories and evaluate the effects of public health response measures, achieving high MenB vaccination coverage is crucial to help protect at-risk persons during outbreaks of meningococcal disease caused by this serogroup.
• Subjects:
  Adolescent Adult Disease Outbreaks Female History, 21St Century Humans Male Meningococcal Infections/Epidemiology Meningococcal Infections/History Meningococcal Infections/Microbiology Meningococcal Infections/Prevention & Control Meningococcal Vaccines Neisseria Meningitidis, Serogroup B Public Health Surveillance Universities Vaccination Vaccination Coverage Young Adult

  More +
• Source:
  Emerg Infect Dis. 25(3):434-440
• Pubmed ID:
  30789140
• Pubmed Central ID:
  PMC6390773
• Document Type:
  Journal Article
• Genre:
  Historical Article
• Place as Subject:
  United States
• Location:
  North America
• Volume:
  25
• Issue:
  3
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:47b7b25206b8d54bb4338ad8e4979ccfc56448be54b7c76f1597514fb3b44aca
• Download URL:
  https://stacks.cdc.gov/view/cdc/76662/cdc_76662_DS1.pdf
• File Type:
  [PDF - 597.33 KB ]