Genomic Analysis of Cardiac Surgery–Associated Mycobacterium chimaera Infections, United States

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Hasan, Nabeeh A. ; Epperson, L. Elaine ; Lawsin, Adrian ; Rodger, Rachael R. ; Perkins, Kiran M. ; Halpin, Alison Laufer ; Perry, K. Allison ; Moulton-Meissner, Heather ; Diekema, Daniel J. ; Crist, Matthew B. ; Perz, Joseph F. ; Salfinger, Max ; Daley, Charles L. ; Strong, Michael
• Description:
  A surgical heater-cooler unit has been implicated as the source for Mycobacterium chimaera infections among cardiac surgery patients in several countries. We isolated M. chimaera from heater-cooler units and patient infections in the United States. Whole-genome sequencing corroborated a risk for these units acting as a reservoir for this pathogen.
• Subjects:
  Cardiac Surgical Procedures / Adverse Effects* Genome, Bacterial* Genomics* / Methods Genotype Humans Mycobacterium / Classification Mycobacterium / Genetics* Mycobacterium Infections / Epidemiology* Mycobacterium Infections / Etiology* Mycobacterium Infections / Microbiology Polymorphism, Single Nucleotide Surgical Wound Infection / Epidemiology* United States / Epidemiology

  More +
• Source:
  Emerg Infect Dis. 25(3):559-563
• Pubmed ID:
  30789131
• Pubmed Central ID:
  PMC6390774
• Document Type:
  Journal Article
• Place as Subject:
  United States
• Volume:
  25
• Issue:
  3
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:12ce9d3fe1ad5ae1defbcf72282aa63465fa4b11ae14cd637fedec460dce30ae
• Download URL:
  https://stacks.cdc.gov/view/cdc/76654/cdc_76654_DS1.pdf
• File Type:
  [PDF - 1.85 MB ]