Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Wansaula, Zimy ; Wortham, Jonathan M. ; Mindra, Godwin ; Haddad, Maryam B. ; Salinas, Jorge L. ; ... More +
Wansaula, Zimy ; Wortham, Jonathan M. ; Mindra, Godwin ; Haddad, Maryam B. ; Salinas, Jorge L. ; Ashkin, David ; Morris, Sapna B. ; Grant, Gail B. ; Ghosh, Smita ; Langer, Adam J. Less -
Description:
Mycobacterium bovis bacillus Calmette-Guérin (BCG) is used as a vaccine to protect against disseminated tuberculosis (TB) and as a treatment for bladder cancer. We describe characteristics of US TB patients reported to the National Tuberculosis Surveillance System (NTSS) whose disease was attributed to BCG. We identified 118 BCG cases and 91,065 TB cases reported to NTSS during 2004-2015. Most patients with BCG were US-born (86%), older (median age 75 years), and non-Hispanic white (81%). Only 17% of BCG cases had pulmonary involvement, in contrast with 84% of TB cases. Epidemiologic features of BCG cases differed from TB cases. Clinicians can use clinical history to discern probable BCG cases from TB cases, enabling optimal clinical management. Public health agencies can use this information to quickly identify probable BCG cases to avoid inappropriately reporting BCG cases to NTSS or expending resources on unnecessary public health interventions.
Subjects:
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Mycobacterium Bovis Public Health Surveillance Synopsis Tuberculosis
Source:
Emerg Infect Dis. 25(3):451-456
Pubmed ID:
30789145
Pubmed Central ID:
PMC6390767
Document Type:
Journal Article
Place as Subject:
United States
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:c72ee691d86b2f171f66505738e1cb425b78421e21a6604c7b7206b6b2ea2a8a
Download URL:
https://stacks.cdc.gov/view/cdc/76636/cdc_76636_DS1.pdf
File Type:

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