Clinical characteristics and outcomes of hematologic malignancy patients with Clostridium difficile toxin immunoassay versus PCR positive test results

Details

• Alternative Title:
  Infect Control Hosp Epidemiol
• Personal Author:
  Ziegler, Matthew ; Landsburg, Daniel ; Pegues, David ; Alby, Kevin ; Gilmar, Cheryl ; Bink, Kristen ; Gorman, Theresa ; Moore, Amy ; Bonhomme, Brittaney ; Omorogbe, Jacqueline ; Tango, Dana ; Tolomeo, Pam ; Han, Jennifer H.
• Description:
  In a cohort of inpatients with hematologic malignancy and positive enzyme immunoassay (EIA) or polymerase chain reaction (PCR) Clostridium difficile tests, we found that clinical characteristics and outcomes were similar between these groups. The method of testing is unlikely to predict infection in this population, and PCR-positive results should be treated with concern.Infect Control Hosp Epidemiol 2018;863-866.
• Subjects:
  Aged Anti-Bacterial Agents Article Bacterial Toxins Clostridioides Difficile Clostridium Infections Feces Female Hematologic Neoplasms Humans Immunoassay Male Middle Aged Polymerase Chain Reaction Retrospective Studies Treatment Outcome

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• Source:
  Infect Control Hosp Epidemiol. 39(7):863-866
• Pubmed ID:
  29690940
• Pubmed Central ID:
  PMC6031467
• Document Type:
  Journal Article
• Funding:
  K01 AI103028/AI/NIAID NIH HHSUnited States/ ; T32 AI055435/AI/NIAID NIH HHSUnited States/ ; U54 CK000485/CK/NCEZID CDC HHSUnited States/
• Volume:
  39
• Issue:
  7
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:5c41e48dbc84d6b748e7975981ffcecdaafc7568dc9684b4747aef78e3ece024
• Download URL:
  https://stacks.cdc.gov/view/cdc/76264/cdc_76264_DS1.pdf
• File Type:
  [PDF - 65.83 KB ]