Identifying Contact Time Required for Secondary Transmission of Clostridioides difficile Infections by Using Real-Time Locating System

Kim, Min Hyung; Kim, Jaewoong; Ra, Heejin; Jeong, Sooyeon; Park, Yoon Soo; Won, Dongju; Lee, Hyukmin; Kim, Heejung

doi:10.3201/eid3005.231588

i

Identifying Contact Time Required for Secondary Transmission of Clostridioides difficile Infections by Using Real-Time Locating System

Supporting Files Public Domain

5 2024
By Kim, Min Hyung ; Kim, Jaewoong ; Ra, Heejin ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Kim, Min Hyung ; Kim, Jaewoong ; Ra, Heejin ; Jeong, Sooyeon ; Park, Yoon Soo ; Won, Dongju ; Lee, Hyukmin ; Kim, Heejung
Description:

Considering patient room shortages and prevalence of other communicable diseases, reassessing the isolation of patients with Clostridioides difficile infection (CDI) is imperative. We conducted a retrospective study to investigate the secondary CDI transmission rate in a hospital in South Korea, where patients with CDI were not isolated. Using data from a real-time locating system and electronic medical records, we investigated patients who had both direct and indirect contact with CDI index patients. The primary outcome was secondary CDI transmission, identified by whole-genome sequencing. Among 909 direct and 2,711 indirect contact cases, 2 instances of secondary transmission were observed (2 [0.05%] of 3,620 cases), 1 transmission via direct contact and 1 via environmental sources. A low level of direct contact (113 minutes) was required for secondary CDI transmission. Our findings support the adoption of exhaustive standard preventive measures, including environmental decontamination, rather than contact isolation of CDI patients in nonoutbreak settings.
Subjects:

Adult Aged Clostridioides Difficile Clostridium Infections Contact Tracing Cross Infection Female Humans Male Middle Aged Retrospective Studies Time Factors
Keywords:

Bacteria Clostridioides Difficile Infection Enteric Infections Horizontal Transmission Of Infectious Diseases Hospital-acquired Infections Patient Isolation Real-time Locating System Secondary Transmission South Korea
Source:

Emerg Infect Dis. 2024; 30(5):908-915
Pubmed ID:

38666567
Pubmed Central ID:

PMC11060456
Document Type:

Journal Article
Place as Subject:

Republic of Korea
Volume:

30
Issue:

5
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:3022dd7a8dcbc7ede7d3c9a7163bae36d08e340bf33e3d4f417ccbc16610aa8d
Download URL:

https://stacks.cdc.gov/view/cdc/154873/cdc_154873_DS1.pdf
File Type:

[PDF - 784.37 KB ]

File Language:

English

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