Details:

Alternative Title:
Vaccine
Personal Author:
Garon, Julie ; Wuddhika, Vong ; Sreenivasan, Nandini ; Wannemuehler, Kathleen ; Vutthikol, Yong ; ... More +
Garon, Julie ; Wuddhika, Vong ; Sreenivasan, Nandini ; Wannemuehler, Kathleen ; Vutthikol, Yong ; Chhorvann, Chhea ; Loharikar, Anagha Less -
Description:
BACKGROUND

In 2017, the Cambodia Ministry of Health introduced human papillomavirus (HPV) vaccine through primarily school-based vaccination targeting 9-year-old girls. Vaccination with a two-dose series of HPV vaccine took place in six districts in two provinces as a demonstration program, to better understand HPV vaccine delivery in Cambodia.

METHODS

We conducted a community-based coverage survey using a one-stage sampling design to evaluate dose-specific vaccination coverage among eligible girls (those born in 2007 and residents in the areas targeted by the campaign). The household-level survey also assessed factors associated with vaccine acceptability and communication strategies. Trained data collectors interviewed caregivers and girls using a standard questionnaire; vaccination cards and health facility records were reviewed.

RESULTS

Of the 7,594 households visited in the two provinces, 315 girls were enrolled in the survey (188 in Siem Reap; 127 in Svay Rieng). Documented two-dose HPV vaccination coverage was 84% (95% confidence interval [CI]: 78%−88%) overall [85% (95% CI: 78%−90%) in Siem Reap; 82% (95% CI: 73%−88%) in Svay Rieng.] Almost all girls (>99%) were reported to be enrolled in school and over 90% of respondents reported receipt of vaccine in school. Knowledge of HPV infection and associated diseases was poor among caregivers and girls; however, 58% of caregivers reported “protection from cervical cancer” as the primary reason for the girl receiving vaccine. No serious adverse events after immunization were reported.

CONCLUSIONS

The HPV vaccine demonstration program in Cambodia achieved high two-dose coverage among eligible girls in both provinces targeted for vaccination in 2017, through primarily school-based vaccination. High school enrollment and strong microplanning and coordination were seen throughout the campaign. Cambodia will use lessons learned from this demonstration project to prepare for scale up to national HPV vaccine introduction.


Subjects:
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Article
Source:
Vaccine. 37(9):1202-1208
Pubmed ID:
30686637
Pubmed Central ID:
PMC6372342
Document Type:
Journal Article
Funding:
CC999999/Intramural CDC HHS/United States
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:3a1bd46ff9ff672cf086ae883a0dcf95509911e3532a45b40a72e9a26f29bdd5
Download URL:
https://stacks.cdc.gov/view/cdc/75921/cdc_75921_DS1.pdf
File Type:

Supporting Files

• nihms-1009550.nxml

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