Ebola Virus Infection Associated with Transmission from Survivors

Den Boon, Saskia; Marston, Barbara J.; Nyenswah, Tolbert G.; Jambai, Amara; Barry, Moumie; Keita, Sakoba; Durski, Kara; Senesie, Schabbethai S.; Perkins, Devin; Shah, Anita; Green, Hugh H.; Hamblion, Esther L.; Lamunu, Margaret; Gasasira, Alex; Mahmoud, Nuha O.; Djingarey, Mamadou H.; Morgan, Oliver; Crozier, Ian; Dye, Christopher

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Ebola Virus Infection Associated with Transmission from Survivors

Published Date:

February 17 2019

Source:

Emerg Infect Dis. 25(2):240-246

Language:

English

[PDF-865.32 KB]

Details:

Alternative Title:

Emerg Infect Dis

Personal Author:

Den Boon, Saskia ; Marston, Barbara J. ; Nyenswah, Tolbert G. ; Jambai, Amara ; Barry, Moumie ; ... More ▼

Description:

Ebola virus (EBOV) can persist in immunologically protected body sites in survivors of Ebola virus disease, creating the potential to initiate new chains of transmission. From the outbreak in West Africa during 2014-2016, we identified 13 possible events of viral persistence-derived transmission of EBOV (VPDTe) and applied predefined criteria to classify transmission events based on the strength of evidence for VPDTe and source and route of transmission. For 8 events, a recipient case was identified; possible source cases were identified for 5 of these 8. For 5 events, a recipient case or chain of transmission could not be confidently determined. Five events met our criteria for sexual transmission (male-to-female). One VPDTe event led to at least 4 generations of cases; transmission was limited after the other events. VPDTe has increased the importance of Ebola survivor services and sustained surveillance and response capacity in regions with previously widespread transmission.

Subject:

[+]

Pubmed ID:

30500321

Pubmed Central ID:

PMC6346469

Document Type:

Journal Article

Place as Subject:

Guinea ; Liberia ; Sierra Leone ;

Collection(s):

Emerging Infectious Diseases

Main Document Checksum:

[+]

Supporting Files:

	18-1011-Techapp-s1.xlsx	application/vnd.openxmlformats-officedocument.spreadsheetml.sheet
	18-1011.nxml	text/xml

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