Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Den Boon, Saskia ; Marston, Barbara J. ; Nyenswah, Tolbert G. ; Jambai, Amara ; Barry, Moumie ; ... More +
Den Boon, Saskia ; Marston, Barbara J. ; Nyenswah, Tolbert G. ; Jambai, Amara ; Barry, Moumie ; Keita, Sakoba ; Durski, Kara ; Senesie, Schabbethai S. ; Perkins, Devin ; Shah, Anita ; Green, Hugh H. ; Hamblion, Esther L. ; Lamunu, Margaret ; Gasasira, Alex ; Mahmoud, Nuha O. ; Djingarey, Mamadou H. ; Morgan, Oliver ; Crozier, Ian ; Dye, Christopher Less -
Description:
Ebola virus (EBOV) can persist in immunologically protected body sites in survivors of Ebola virus disease, creating the potential to initiate new chains of transmission. From the outbreak in West Africa during 2014-2016, we identified 13 possible events of viral persistence-derived transmission of EBOV (VPDTe) and applied predefined criteria to classify transmission events based on the strength of evidence for VPDTe and source and route of transmission. For 8 events, a recipient case was identified; possible source cases were identified for 5 of these 8. For 5 events, a recipient case or chain of transmission could not be confidently determined. Five events met our criteria for sexual transmission (male-to-female). One VPDTe event led to at least 4 generations of cases; transmission was limited after the other events. VPDTe has increased the importance of Ebola survivor services and sustained surveillance and response capacity in regions with previously widespread transmission.
Subject:
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Ebolavirus Expedited Hemorrhagic Fever, Ebola Response Sexual Transmission Surveillance Survivors Synopsis Viral Persistence
Source:
Emerg Infect Dis. 25(2):240-246
Pubmed ID:
30500321
Pubmed Central ID:
PMC6346469
Document Type:
Journal Article
Place as Subject:
Guinea ; Liberia ; Sierra Leone
Guinea ; Liberia ; Sierra Leone Less -
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:7c46cde7a9fbde5915af2e03c23e1c69ac79344174eafa50940f1ec2cd1d7739
Download URL:
https://stacks.cdc.gov/view/cdc/75851/cdc_75851_DS1.pdf
File Type:

Supporting Files

• 	18-1011-Techapp-s1.xlsx	xlsx
  	18-1011.nxml	xml

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