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Updated U.S. Public Health Service guidelines for the management of occupational exposures to HIV and recommendations for postexposure prophylaxis
Filetype[PDF-266.48 KB]


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This document has replaced (most recent first):
  1. Update: Provisional Public Health Service recommendations for chemoprophylaxis after occupational exposure to HIV
    Published:
    June 7, 1996
    Source:
    MMWR. Morbidity and mortality weekly report. 1996; 45(22):468-80.
    Description:
    Although preventing blood exposures is the primary means of preventing occupationally acquired human immunodeficiency virus (HIV) infection, appropriate postexposure management is an important element of workplace safety. Information suggesting that ...
    Status:
    superseded
    File Type:
    Filetype[PDF - 284.04 KB]
  2. Guidelines to prevent simian immunodeficiency virus infection in laboratory workers and animal handlers
    Corporate Author:
    National Center for Infectious Diseases (U.S.). Division of HIV/AIDS.
    Published:
    November 18, 1988
    Source:
    MMWR. Morbidity and mortality weekly report. 1988; 37(45):693-4, 699-704.
    Description:
    The human T-lymphotropic viruses, type I (HTLV-I) and type II (HTLV-II), are closely related but distinct retroviruses that can infect humans. They are different from the human immunodeficiency viruses that cause acquired immunodeficiency syndrome. S...
    Status:
    superseded
    File Type:
    Filetype[HTML]
  3. Public Health Service guidelines for the management of health-care worker exposures to HIV and recommendations for postexposure prophylaxis
    Personal Author:
    Bell, David M.; Cardo, Denise M.; Chiarello, Linda.; Kaplan, Jonathan E.; Martin, Linda S.; Panlilio, Adelisa L.;
    Corporate Author:
    Centers for Disease Control and Prevention (U.S.); Hospital Infections Program (U.S.); National Center for Infectious Diseases (U.S.), Division of AIDS, STD, and TB Laboratory Research.; National Institute for Occupational Safety and Health;
    Published:
    May 15, 1998
    Series:
    MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports ; v. 47, no. RR-7
    Description:
    This report updates and consolidates all previous PHS recommendations for the management of health-care workers (HCWs) who have occupational exposure to blood and other body fluids that may contain human immunodeficiency virus (HIV); it includes reco...
    Status:
    superseded
    File Type:
    Filetype[PDF - 374.82 KB]
  4. Updated U.S. Public Health Service guidelines for the management of occupational exposures to HBV, HCV, and HIV and recommendations for postexposure prophylaxis
    Personal Author:
    Alter, Miriam J.; Alvarado-Ramy, Francisco; Beltrami, Elise M.; Bower, William A.; Cardo, Denise M.; Critchley, Sara E.; Kaplan, Jonathan E.; Lushniak, Boris D.; Panlilio, Adelisa L.;
    Corporate Author:
    Centers for Diseases Control and Prevention (U.S.); National Center for HIV, STD, and TB Prevention (U.S.); National Center for Infectious Diseases (U.S.); National Institute for Occupational Safety and Health Division of Surveillance, Hazard Evaluations, and Field Studies;
    Published:
    June 29, 2001
    Source:
    MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports / Centers for Disease Control. 2001; 50(RR-11):1-52.
    Series:
    MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports ; v. 50, no. RR-11
    Description:
    This report updates and consolidates all previous U.S. Public Health Service recommendations for the management of health-care personnel (HCP) who have occupational exposure to blood and other body fluids that might contain hepatitis B virus (HBV), h...
    Status:
    superseded
    File Type:
    Filetype[PDF - 333.49 KB]
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  1. Updated U.S. Public Health Service guidelines for the management of occupational exposures to HIV and recommendations for postexposure prophylaxis.
    Personal Author:
    Kuhar, David T.; Henderson, David K.; Struble, Kimberly A.; Heneine, Walid; Thomas, Vasavi; Cheever, Laura W.; Gomaa, Ahmed; Panlilio, Adelisa L.;
    Corporate Author:
    USPHS Working Group on Occupational Postexposure Prophylaxis.; National Center for Emerging and Zoonotic Infectious Diseases (U.S.). Division of Healthcare Quality Promotion.;
    Published:
    9/25/2013 Update (May 23, 2018)
    Description:
    Interim Statement Regarding Potential Fetal Harm from Exposure to Dolutegravir – Implications for HIV Post-exposure Prophylaxis (PEP). Please see attached statement (PDF of Dolutegravir attached). : Several corrections have been made to this PDF si...
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  2. Updated U.S. Public Health Service guidelines for the management of occupational exposures to HBV, HCV, and HIV and recommendations for postexposure prophylaxis
    Personal Author:
    Alter, Miriam J.; Alvarado-Ramy, Francisco; Beltrami, Elise M.; Bower, William A.; Cardo, Denise M.; Critchley, Sara E.; Kaplan, Jonathan E.; Lushniak, Boris D.; Panlilio, Adelisa L.;
    Corporate Author:
    Centers for Diseases Control and Prevention (U.S.); National Center for HIV, STD, and TB Prevention (U.S.); National Center for Infectious Diseases (U.S.); National Institute for Occupational Safety and Health Division of Surveillance, Hazard Evaluations, and Field Studies;
    Published:
    June 29, 2001
    Source:
    MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports / Centers for Disease Control. 2001; 50(RR-11):1-52.
    Series:
    MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports ; v. 50, no. RR-11
    Description:
    This report updates and consolidates all previous U.S. Public Health Service recommendations for the management of health-care personnel (HCP) who have occupational exposure to blood and other body fluids that might contain hepatitis B virus (HBV), h...
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    superseded
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  3. Recommendations for postexposure interventions to prevent infection with hepatitis B virus, hepatitis C virus, or human immunodeficiency virus, and tetanus in persons wounded during bombings and other mass-casualty events -- United States, 2008
    Personal Author:
    Chapman, Louisa E.; Hunt, Richard C.; Sullivent, Ernest E.; Grohskopf, Lisa A.; Kilmarx, Peter H.; Perz, Joseph F.; Thompson, Nicola D.; Beltrami, Elise M.; Panlilio, Adelisa L.; Kretsinger, Katrina; Ehrenberg, Richard L.;
    Corporate Author:
    Centers for Disease Control and Prevention (U.S), Coordinating Office for Terrorism Preparedness and Emergency Response.; National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (U.S.); National Center for Immunization and Respiratory Diseases (U.S.); National Center for Injury Prevention and Control (U.S.), Division of Injury Response.; National Center for Preparedness, Detection, and Control of Infectious Diseases (U.S.); National Institute for Occupational Safety and Health;
    Published:
    August 1, 2008
    Series:
    MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports ; v. 57, no. RR-6 PMID:18668022:MODS 18668022
    Description:
    "This report outlines recommendations for postexposure interventions to prevent infection with hepatitis B virus, hepatitis C virus, or human immunodeficiency virus, and tetanus in persons wounded during bombings or other events resulting in mass cas...
    Status:
    current
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  4. Antiretroviral postexposure prophylaxis after sexual, injection-drug use, or other nonoccupational exposure to HIV in the United States; recommendations from the U.S. Department of Health and Human Services
    Personal Author:
    Auerbach, Judith D.; Black, Roberta J.; Cheever, Laura.; Greenberg, Alan E.; Grohskopf, Lisa A.; Johnson, Michael; Onorato, Ida M.; Paxton, Lynn A.; Smith, Dawn K.; Struble, Kimberly A.; Veronese, Fulvia;
    Corporate Author:
    National Center for HIV, STD, and TB Prevention (U.S.), Division of HIV/AIDS Prevention.; Centers for Disease Control and Prevention (U.S.);
    Published:
    January 21, 2005
    Series:
    MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports ; v. 54, no. RR-2
    Description:
    The most effective means of preventing human immunodeficiency virus (HIV) infection is preventing exposure. The provision of antiretroviral drugs to prevent HIV infection after unanticipated sexual or injection-drug--use exposure might be beneficial....
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  5. Updated guidelines for antiretroviral postexposure prophylaxis after sexual, injection drug use, or other nonoccupational exposure to HIV—United States, 2016
    Personal Author:
    Dominguez, Kenneth L.; Smith, Dawn K.; Vasavi Thomas,; Crepaz, Nicole; Lang, Karen; Heneine, Walid; McNicholl, Janet M.; Reid, Laurie; Freelon, Brandi; Nesheim, Steven R.; Huang, Ya-lin (Aileen); Weidle, Paul J.;
    Published:
    April 18, 2016, Update (May 23, 2018)
    Description:
    Interim Statement Regarding Potential Fetal Harm from Exposure to Dolutegravir – Implications for HIV Post-exposure Prophylaxis (PEP). Please see attached statement (PDF of Dolutegravir attached) : From the Centers for Disease Control and Preventio...
    Status:
    current
    File Type:
    Filetype[PDF - 1.17 MB]