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Genetics and biological markers of risk for alcoholism.
  • Published Date:
    1988 Nov-Dec
  • Source:
    Public Health Rep. 103(6):690-698
  • Language:
    English
Filetype[PDF-1.73 MB]


Details:
  • Alternative Title:
    Public Health Rep
  • Personal Author:
  • Description:
    Substantial scientific evidence has accumulated that both genetic and environmental factors predispose the development of alcoholism in certain individuals. Evidence has accumulated to indicate that alcoholism is a heterogeneous entity arising from multiple etiologies. The demonstrated role of genetics in increasing the risk of alcoholism has promoted the search for biological markers that could objectively identify individuals who are genetically predisposed to alcoholism. Identifying such markers could allow for early diagnosis, focused prevention, and differential and type-specific treatment of alcoholism. Promising markers have been provided by research in electrophysiology, endocrinology, and biochemistry. Recent advances in molecular genetics are offering prospects for direct analysis of the human genome to determine elements that provide predisposition to, and protection from, alcoholism. Recent advances in research and new knowledge gained by the alcoholism treatment community and the lay public are helping to diminish the societal damage caused by alcohol abuse and alcoholism and to change prevailing attitudes about them.

  • Subject:
  • Pubmed ID:
    3141966
  • Pubmed Central ID:
    PMCnull
  • Document Type:
    Journal Article
  • Collection(s):
    Public Health Reports
  • Main Document Checksum:
  • Supporting Files:
    No Additional Files
    1. Alcohol and highway safety in a public health perspective.
      Personal Author:
      Dickman, F B
      Published Date:
      1988 Nov-Dec
      Source:
      Public Health Rep. 103(6):653-658
      Description:
      The Public Health Service and the National Highway Traffic Safety Administration share the responsibility for problems related to injury prevention and control regarding the alcohol-impaired operation of motor vehicles. NHTSA activities have evolved ...
      File Type:
      Filetype[PDF - 1.44 MB]
    2. Alcoholism research: delivering on the promise.
      Personal Author:
      Goodwin, F K
      Published Date:
      1988 Nov-Dec
      Source:
      Public Health Rep. 103(6):569-574
      Description:
      Prospects for research advances in alcoholism are very promising, because of the explosion in the neurosciences and advances in epidemiology and typology of the disorder. For example, the field is now ready for molecular genetics studies of the early...
      File Type:
      Filetype[PDF - 1.67 MB]
    3. Alcohol-related birth defects: an update.
      Personal Author:
      Warren, K R; Bast, R J;
      Published Date:
      1988 Nov-Dec
      Source:
      Public Health Rep. 103(6):638-642
      Description:
      Historically, mankind has at least suspected that alcohol was somehow connected with undesirable effects on progeny. In the 18th century, physicians became aware that maternal alcohol consumption resulted in excess fetal and neonatal mortality, low b...
      File Type:
      Filetype[PDF - 927.92 KB]
    4. A perspective on science and public health policy.
      Personal Author:
      Gordis, E
      Published Date:
      1988 Nov-Dec
      Source:
      Public Health Rep. 103(6):575-577
      File Type:
      Filetype[PDF - 899.87 KB]
    5. Public Health Reports ; v. 103, no. 6 : 1988 subject and author index
      Published Date:
      Nov-Dec 1988
      Source:
      Public Health Rep. 103(6)
      Description:
      Index and masthead
      File Type:
      Filetype[PDF - 3.14 MB]
    6. Public Health Reports ; v. 103, no. 6 : table of contents
      Published Date:
      Nov-Dec 1988
      Source:
      Public Health Rep. 103(6)
      File Type:
      Filetype[PDF - 419.09 KB]
    7. Effects of legislative reform to reduce drunken driving and alcohol-related traffic fatalities.
      Personal Author:
      Hingson, R W; Howland, J; Levenson, S;
      Published Date:
      1988 Nov-Dec
      Source:
      Public Health Rep. 103(6):659-667
      Description:
      From 1980 through 1985, considerable progress was made across the Nation in reducing drunken driving and fatal automobile crashes. More than 400 chapters of local citizen groups concerned with reducing drunken driving were formed. New media coverage,...
      File Type:
      Filetype[PDF - 2.12 MB]
    8. NATIONAL CENTER FOR HEALTH STATISTICS: DATA LINE
      Published Date:
      Nov 1988
      Source:
      Public Health Rep. 103(6):713-714
      File Type:
      Filetype[PDF - 423.81 KB]
    9. Biological features of women's alcohol use: a review.
      Personal Author:
      Roman, P M
      Published Date:
      1988 Nov-Dec
      Source:
      Public Health Rep. 103(6):628-637
      Description:
      Sensitivity to gender issues in the research community has generated a modest but growing amount of data on the biological effects of alcohol consumption on women. Data generally indicate that the same amounts of alcohol have greater effects on women...
      File Type:
      Filetype[PDF - 2.02 MB]
    10. Screening for alcoholism: techniques and issues.
      Personal Author:
      Allen, J P; Eckardt, M J; Wallen, J;
      Published Date:
      1988 Nov-Dec
      Source:
      Public Health Rep. 103(6):586-592
      Description:
      Alcoholism is an often overlooked health problem because alcoholics usually do not seek treatment for their drinking problems. They do, however, seek general medical care for other health reasons, and a number of screening techniques have proven usef...
      File Type:
      Filetype[PDF - 1.49 MB]
    11. Alcohol problem resources and services in State supported programs, FY 1987.
      Personal Author:
      Butynski, W; Canova, D M;
      Published Date:
      1988 Nov-Dec
      Source:
      Public Health Rep. 103(6):611-620
      Description:
      During fiscal year 1987, expenditures for alcohol and drug abuse services in facilities receiving at least some funds from State alcohol and drug agencies totaled $1,809,749,013. Of this total, approximately 51.1 percent was contributed by State gove...
      File Type:
      Filetype[PDF - 1.81 MB]
    12. Raising public awareness about the extent of alcohol-related problems: an overview.
      Personal Author:
      Bowen, O R
      Published Date:
      1988 Nov-Dec
      Source:
      Public Health Rep. 103(6):559-563
      File Type:
      Filetype[PDF - 1.15 MB]
    13. Trends in alcohol-related morbidity and mortality.
      Personal Author:
      Williams, G D; Grant, B F; Stinson, F S; Zobeck, T S; Aitken, S S; Noble, J;
      Published Date:
      1988 Nov-Dec
      Source:
      Public Health Rep. 103(6):592-597
      Description:
      Two major trends regarding alcohol use and consequences of alcohol abuse in the United States are showing significant improvement. Continued declines are evident in age-adjusted rates of liver cirrhosis mortality, and per capita alcohol consumption i...
      File Type:
      Filetype[PDF - 1.53 MB]
    14. The economic impact of alcohol abuse and alcoholism.
      Personal Author:
      Burke, T R
      Published Date:
      1988 Nov-Dec
      Source:
      Public Health Rep. 103(6):564-568
      Description:
      The economic effects of alcohol abuse are as damaging to the nation as the health effects, affecting the family, the community, and persons of all ages. Underaged drinking is interfering with children's development, affecting the nation's ability to ...
      File Type:
      Filetype[PDF - 1.10 MB]
    15. A biobehavioral research perspective on alcohol abuse and alcoholism.
      Personal Author:
      Brady, J V
      Published Date:
      1988 Nov-Dec
      Source:
      Public Health Rep. 103(6):699-707
      Description:
      An empirical biobehavioral research approach to the conditions generally identified as alcohol abuse and alcoholism emphasizes the temporal ordering of participating biochemical, physiological, and behavioral events that provide an operational basis ...
      File Type:
      Filetype[PDF - 2.01 MB]
    16. The role of alcohol in suicides in Erie County, NY, 1972-84.
      Personal Author:
      Welte, J W; Abel, E L; Wieczorek, W;
      Published Date:
      1988 Nov-Dec
      Source:
      Public Health Rep. 103(6):648-652
      Description:
      A discriminant analysis of the 806 suicide victims in Erie County, NY, from 1972-84, compared those with alcohol in the blood to those without. Thirty-three percent of the victims had alcohol in their blood. Those with blood alcohol present were more...
      File Type:
      Filetype[PDF - 791.43 KB]
    17. Theories and models supporting prevention approaches to alcohol problems among youth.
      Personal Author:
      Johnson, E M; Amatetti, S; Funkhouser, J E; Johnson, S;
      Published Date:
      1988 Nov-Dec
      Source:
      Public Health Rep. 103(6):578-586
      Description:
      The Alcohol, Drug Abuse, and Mental Health Administration's Office for Substance Abuse Prevention (OSAP) was established to initiate programs to provide prevention and early intervention services for young people, especially high-risk youth. OSAP's s...
      File Type:
      Filetype[PDF - 1.75 MB]
    18. Children of alcoholics: helping a vulnerable group.
      Personal Author:
      Woodside, M
      Published Date:
      1988 Nov-Dec
      Source:
      Public Health Rep. 103(6):643-648
      Description:
      There are 28 million children of alcoholics in the United States--1 of every 8 Americans. They are more likely than others to suffer from alcoholism and a wide range of physical, emotional, and mental health problems. It is probable that an inherited...
      File Type:
      Filetype[PDF - 1.34 MB]
    19. Assessment of the potential for surveillance of alcohol-related casualties using National Hospital Discharge Survey data.
      Personal Author:
      Towle, L H; Stinson, F S; Dufour, M;
      Published Date:
      1988 Nov-Dec
      Source:
      Public Health Rep. 103(6):597-605
      Description:
      It is well known that alcohol abuse is significantly involved in the incidence of casualties (that is, accidents and injuries as they are defined for the purpose of coding diagnoses in the International Classification of Diseases). Thus, a study was ...
      File Type:
      Filetype[PDF - 1.94 MB]
    20. Research on alcohol problems from the perspective of changes--1940 to 1990.
      Personal Author:
      Straus, R
      Published Date:
      1988 Nov-Dec
      Source:
      Public Health Rep. 103(6):707-712
      Description:
      The nature of alcohol problems, knowledge about alcohol use and abuse, and public perceptions and responses have all undergone substantial change during the past half-century. This paper traces some interrelationships between changes in alcohol-speci...
      File Type:
      Filetype[PDF - 1.38 MB]
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