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Genetic counseling in sickle cell anemia: experiences with couples at risk.
  • Published Date:
    1988 Mar-Apr
  • Source:
    Public Health Rep. 103(2):174-178
  • Language:
    English
Filetype[PDF-964.37 KB]


Details:
  • Alternative Title:
    Public Health Rep
  • Personal Author:
  • Description:
    Beginning in 1970, a cohort of 74 sickle trait-carrying couples was identified who risked producing children with sickle cell anemia or other serious hemoglobinopathies. They were counseled concerning the disease and their risk, and their initial reactions, their stated intentions concerning birth control and childbearing, and their subsequent childbearing histories were documented. Initial responses to the risk information varied widely, and stated intentions of birth control or childbearing did not accurately predict subsequent childbearing. Among 25 couples for whom there were complete childbearing data, there were 31 pregnancies with 13 affected children prior to counseling. After counseling, there were 25 pregnancies resulting in 10 affected children. The majority of the subsequent pregnancies occurred in the group who had not borne children or an affected child before counseling. In young couples, concern for producing a child with sickle cell anemia is often offset by a strong desire to have children regardless of risk.

  • Subject:
  • Pubmed ID:
    3128834
  • Pubmed Central ID:
    PMCnull
  • Document Type:
    Journal Article
  • Collection(s):
    Public Health Reports
  • Main Document Checksum:
  • Supporting Files:
    No Additional Files
    1. PROGRAMS, PRACTICES, PEOPLE
      Published Date:
      1988 Mar-Apr
      Source:
      Public Health Rep. 103(2):204-208
      File Type:
      Filetype[PDF - 999.96 KB]
    2. Public Health Rep ; v. 103, no. 2 : Masthead
      Published Date:
      Mar-Apr 1988
      Source:
      Public Health Rep. 103(2)
      File Type:
      Filetype[PDF - 1.85 MB]
    3. Validation of maternally reported birth weights among 46,637 Tennessee WIC program participants.
      Personal Author:
      Gayle, H D; Yip, R; Frank, M J; Nieburg, P; Binkin, N J;
      Published Date:
      1988 Mar-Apr
      Source:
      Public Health Rep. 103(2):143-147
      Description:
      To assess the accuracy of maternally reported birth weights, we compared birth weights reported by mothers in the Tennessee Women, Infants, and Children Supplemental Feeding Program (WIC) from 1975 to 1984 with the birth weights recorded on the corre...
      File Type:
      Filetype[PDF - 791.81 KB]
    4. Public Health Rep
      Published Date:
      Mar-Apr 1988
      File Type:
      Filetype[PDF - 658.41 KB]
    5. How people obtain their health information--a survey in two Pennsylvania counties.
      Personal Author:
      Connell, C M; Crawford, C O;
      Published Date:
      1988 Mar-Apr
      Source:
      Public Health Rep. 103(2):189-195
      Description:
      A sample of 182 respondents to a mail survey in two Pennsylvania counties, one rural, one urban, provided information on the sources of their health information. Research questions addressed were from what sources did they obtain their health informa...
      File Type:
      Filetype[PDF - 1.10 MB]
    6. NATIONAL CENTER FOR HEALTH STATISTICS: DATA LINE
      Published Date:
      Mar 1988
      Source:
      Public Health Rep. 103(2):202-203
      File Type:
      Filetype[PDF - 603.77 KB]
    7. Smoking and children.
      Personal Author:
      Windom, R E
      Published Date:
      1988 Mar-Apr
      Source:
      Public Health Rep. 103(2):105
      File Type:
      Filetype[PDF - 118.40 KB]
    8. Factors affecting the supply of minority physicians in 2000.
      Personal Author:
      Simpson, C E; Aronoff, R;
      Published Date:
      1988 Mar-Apr
      Source:
      Public Health Rep. 103(2):178-184
      Description:
      There was a substantial increase in the number of black and Hispanic physicians between 1970 and 1985. During the next 15 years, 1985 to 2000, the increase is projected to continue. The factors that will determine the size of the increase and the cha...
      File Type:
      Filetype[PDF - 1.22 MB]
    9. Preparing and presenting an introductory course on motor vehicle injury.
      Personal Author:
      Holden, J A; Christoffel, T;
      Published Date:
      1988 Mar-Apr
      Source:
      Public Health Rep. 103(2):153-161
      Description:
      Health professionals are key to any progress in reducing motor vehicle injury and death, yet they have been slow to recognize their role in this important area. One factor contributing to this problem has been the absence of courses on motor vehicle ...
      File Type:
      Filetype[PDF - 1.97 MB]
    10. Assessing trends in mortality in 121 U.S. cities, 1970-79, from all causes and from pneumonia and influenza.
      Personal Author:
      Baron, Roy C.; Dicker, Richard C.; Bussell, Kelley E.; Herndon, Joy L.;
      Published Date:
      1988 Mar-Apr
      Source:
      Public Health Rep. 103(2):120-128
      Description:
      The Centers for Disease Control receives weekly reports of mortality due to all causes and to pneumonia and influenza from 121 cities and counties in the United States. To assess the epidemiologic applicability of these data, the trends of death rate...
      File Type:
      Filetype[PDF - 2.75 MB]
    11. Risk for measles related to immunization status in two Tucson high schools.
      Personal Author:
      McCombie, S C; Worrell, R D; Porter, B W; Browning, J A; Ray, C G;
      Published Date:
      1988 Mar-Apr
      Source:
      Public Health Rep. 103(2):162-166
      Description:
      An outbreak of measles occurred in Tucson, AZ, in 1985; 112 of the 225 cases were among students at two large high schools. A review of the immunization records of all students at both schools was undertaken in order to assess the risk of a person co...
      File Type:
      Filetype[PDF - 1.01 MB]
    12. A health survey of Klamath Indian elders 30 years after the loss of tribal status.
      Personal Author:
      Joos, S K; Ewart, S;
      Published Date:
      1988 Mar-Apr
      Source:
      Public Health Rep. 103(2):166-173
      Description:
      Federal recognition of the tribal status of the Klamath Indians of Oregon was terminated by Congress in 1954, along with all health, education, and welfare services. In the winter and spring of 1985 a health status and health care needs assessment wa...
      File Type:
      Filetype[PDF - 1.21 MB]
    13. Employee smoking behavior changes and attitudes following a restrictive policy on worksite smoking in a large company.
      Personal Author:
      Petersen, L R; Helgerson, S D; Gibbons, C M; Calhoun, C R; Ciacco, K H; Pitchford, K C;
      Published Date:
      1988 Mar-Apr
      Source:
      Public Health Rep. 103(2):115-120
      Description:
      A Connecticut insurance company adopted a policy prohibiting smoking in all work areas. Three months later, the authors assessed smoking behavior changes and attitudes of a sample of 1,210 employees, 56.6 percent of the total. The survey showed that ...
      File Type:
      Filetype[PDF - 1.20 MB]
    14. Cancer mortality among Mexican immigrants in the United States.
      Personal Author:
      Rosenwaike, I
      Published Date:
      1988 Mar-Apr
      Source:
      Public Health Rep. 103(2):195-201
      Description:
      In 1980 there were more than 2 million Mexican-born immigrants living in the United States. Mortality statistics for 1979-81 indicate that the standardized mortality ratio for cancer among Mexican immigrants is 72 percent of that among all white male...
      File Type:
      Filetype[PDF - 1.35 MB]
    15. Public Health Rep ; v. 103, no. 2 : table of contents
      Published Date:
      Mar-Apr 1988
      Source:
      Public Health Rep. 103(2)
      File Type:
      Filetype[PDF - 442.79 KB]
    16. The Area Resource File--a brief look.
      Personal Author:
      Stambler, H V
      Published Date:
      1988 Mar-Apr
      Source:
      Public Health Rep. 103(2):184-188
      File Type:
      Filetype[PDF - 1.32 MB]
    17. MATCH: a maternal and child health information network.
      Personal Author:
      Platt, L J; Benford, M S;
      Published Date:
      1988 Mar-Apr
      Source:
      Public Health Rep. 103(2):147-153
      Description:
      The Maternal and Child Health Information Network--MATCH--was begun in 1984 as a demonstration project with support from the Division of Maternal and Child Health of the Health Resources and Services Administration, Public Health Service. The primary...
      File Type:
      Filetype[PDF - 1.24 MB]
    18. Estimates of incidence and costs of intestinal infectious diseases in the United States.
      Personal Author:
      Garthright, W E; Archer, D L; Kvenberg, J E;
      Published Date:
      1988 Mar-Apr
      Source:
      Public Health Rep. 103(2):107-115
      Description:
      The incidence of acute episodes of intestinal infectious diseases in the United States was estimated through analysis of community-based studies and national interview surveys. Their differing results were reconciled by adjusting the study population...
      File Type:
      Filetype[PDF - 1.40 MB]
    19. Economic status differences in infant mortality by cause of death.
      Personal Author:
      Stockwell, E G; Swanson, D A; Wicks, J W;
      Published Date:
      1988 Mar-Apr
      Source:
      Public Health Rep. 103(2):135-142
      Description:
      Infant mortality differentials in a metropolitan aggregate of eight Ohio cities were examined for the years 1979-81. The primary analytical unit was the census tract of mother's usual residence. The independent variable was defined as the percentage ...
      File Type:
      Filetype[PDF - 1.45 MB]
    20. After Chernobyl--how U.S. physicians respond to radioactive fallout.
      Personal Author:
      Winder, A E; Stanitis, M A; Stoddard, A M;
      Published Date:
      1988 Mar-Apr
      Source:
      Public Health Rep. 103(2):128-135
      Description:
      On April 26, 1986, a reactor unit at the Soviet Union's Chernobyl Power Station exploded, and substantial amounts of radioactive material were released. Fallout from this incident was deposited in the United States and elsewhere. Radioactive fallout ...
      File Type:
      Filetype[PDF - 1.37 MB]
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