Details:

Alternative Title:
J Agric Biol Environ Stat
Personal Author:
Hepworth, Graham ; Biggerstaff, Brad J.
Hepworth, Graham ; Biggerstaff, Brad J. Less -
Description:
In the estimation of proportions by pooled testing, the MLE is biased, and several methods of correcting the bias have been presented in previous studies. We propose a new estimator based on the bias correction method introduced by Firth (Biometrika 80:27-38, 1993), which uses a modification of the score function, and we provide an easily computable, Newton-Raphson iterative formula for its computation. Our proposed estimator is almost unbiased across a range of problems, and superior to existing methods. We show that for equal pool sizes the new estimator is equivalent to the estimator proposed by Burrows (Phytopathology 77:363-365, 1987). The performance of our estimator is examined using pooled testing problems encountered in plant disease assessment and prevalence estimation of mosquito-borne viruses.
Subject:
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Article
Bias Correction
Estimation Of Proportions
Group Testing
Pooled Testing
Virus Prevalence

Source:
J Agric Biol Environ Stat. 22(4):602-614
Pubmed ID:
30636859
Pubmed Central ID:
PMC6325642
Document Type:
Journal Article
Funding:
CC999999/Intramural CDC HHS/United States
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:c125771aff34be2fe16341fb3efed9c87e5b874e12e878041e021b69c2326f97
File Type:

Supporting Files

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