Crimean-Congo Hemorrhagic Fever Virus, Mongolia, 2013–2014

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Voorhees, Matthew A. ; Padilla, Susana L. ; Jamsransuren, Dulamjav ; Koehler, Jeffrey W. ; Delp, Korey L. ; Adiyadorj, Dolgorkhand ; Baasandagwa, Uyanga ; Jigjav, Battsetseg ; Olschner, Scott P. ; Minogue, Timothy D. ; Schoepp, Randal J.
• Description:
  During 2013-2014, we collected 1,926 serum samples from humans and 4,583 ticks (Hyalomma asiaticum or Dermacentor nuttalli) in select regions of Mongolia to determine the risk for Crimean-Congo hemorrhagic fever virus (CCHFV) infection among humans in this country. Testing of human serum samples by ELISA demonstrated an overall CCHFV antibody prevalence of 1.4%; Bayankhongor Province had the highest prevalence, 2.63%. We pooled and analyzed tick specimens by real-time reverse transcription PCR; 1 CCHFV-positive H. asiaticum tick pool from Ömnögovi was identified. In phylogenetic analyses, the virus's partial small segment clustered with CCHFV isolates from Central Asia, and the complete medium segment grouped with CCHFV isolates from Africa, Asia, and the Middle East. This study confirms CCHFV endemicity in Mongolia and provides information on risk for CCHFV infection. Further research is needed to better define the risk for CCHFV disease to improve risk mitigation, diagnostics, and surveillance.
• Subjects:
  Animals Antibodies, Neutralizing Antibodies, Viral Computational Biology Geography, Medical Hemorrhagic Fever, Crimean/Epidemiology Hemorrhagic Fever, Crimean/History Hemorrhagic Fever, Crimean/Transmission Hemorrhagic Fever, Crimean/Virology Hemorrhagic Fever Virus, Crimean-Congo History, 21St Century Humans Immunoglobulin G Neutralization Tests Phylogeny Rna, Viral Sequence Analysis, DNA Serologic Tests Ticks

  More +
• Source:
  Emerg Infect Dis. 24(12):2202-2209
• Pubmed ID:
  30457521
• Pubmed Central ID:
  PMC6256378
• Document Type:
  Journal Article
• Genre:
  Historical Article
• Place as Subject:
  Mongolia
• Volume:
  24
• Issue:
  12
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:0a81d186c523161fe601fcd0e2e1fa93c53a4698c06214e0d57a563a0efdcf20
• Download URL:
  https://stacks.cdc.gov/view/cdc/61335/cdc_61335_DS1.pdf
• File Type:
  [PDF - 909.62 KB ]