Burkholderia lata Infections from Intrinsically Contaminated Chlorhexidine Mouthwash, Australia, 2016

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Leong, Lex E.X. ; Lagana, Diana ; Carter, Glen P. ; Wang, Qinning ; Smith, Kija ; Stinear, Tim P. ; Shaw, David ; Sintchenko, Vitali ; Wesselingh, Steven L. ; Bastian, Ivan ; Rogers, Geraint B.
• Description:
  Burkholderia lata was isolated from 8 intensive care patients at 2 tertiary hospitals in Australia. Whole-genome sequencing demonstrated that clinical and environmental isolates originated from a batch of contaminated commercial chlorhexidine mouthwash. Genomic analysis identified efflux pump-encoding genes as potential facilitators of bacterial persistence within this biocide.
• Subjects:
  Burkholderia Burkholderia Infections Chlorhexidine Cross Infection Disease Outbreaks Disinfectants Humans Intensive Care Units Mouthwashes Phylogeny Polymorphism, Single Nucleotide Tertiary Care Centers Whole Genome Sequencing

  More +
• Source:
  Emerg Infect Dis. 24(11):2109-2111
• Pubmed ID:
  30334703
• Pubmed Central ID:
  PMC6199994
• Document Type:
  Journal Article
• Genre:
  Letter
• Place as Subject:
  Australia
• Volume:
  24
• Issue:
  11
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:90272be80d770bb48ea7fe0dcea2e201c34c399125fea4b9828b3545e0c82993
• Download URL:
  https://stacks.cdc.gov/view/cdc/60381/cdc_60381_DS1.pdf
• File Type:
  [PDF - 454.24 KB ]