Longitudinal association between eating frequency and HbA1c and serum lipids in diabetes in the SEARCH for Diabetes in Youth Study

Details

• Alternative Title:
  Pediatr Diabetes
• Personal Author:
  Li, Chao ; D’Agostino, Ralph B. ; Dabelea, Dana ; Liese, Angela D. ; Mayer-Davis, Elizabeth J. ; Pate, Russell ; Merchant, Anwar T.
• Description:
  Background
  
  Few studies have evaluated the prospective association of eating frequency with HbA1c levels and cardiovascular disease risk markers among youth with diabetes.
  
  Objective
  
  To examine the 5-year longitudinal association of eating frequency with HbA1c and serum lipid levels among youth with type 1 diabetes (T1D) or type 2 diabetes (T2D).
  
  Methods
  
  1,049 youth (≥10 years old) with incident T1D (n=821) or T2D (n=228) who participated in the SEARCH for Diabetes in Youth Study were included. Eating frequency (≤3, 4-5 or 6-10 times/day) measured at baseline and follow-up visits was related to HbA1c and serum lipid levels measured repeatedly over 5 years.
  
  Results
  
  Increased eating frequency was associated with larger increases in HbA1c among youth T1D. For example, for youth with T1D who ate ≤ 3 times/day at the outset and ate 6-10 times/day 5 years later, the longitudinal model predicted greater absolute increases in HbA1c (2.77%); whereas for youth with T1D who ate 6-10 times/day at the outset and ate ≤3 times/day 5 years later, the model predicted lesser absolute increases in HbA1c (1.33%). Eating frequency was not associated with changes in serum lipid levels among youth with T1D or T2D.
  
  Conclusions
  
  Youth with T1D who increased their eating frequency vs. those who decreased it had larger increases in HbA1c over 5 years.
  
  
• Subjects:
  Article Diabetes Eating Frequency Longitudinal Analysis And Nutrition Youth
• Source:
  Pediatr Diabetes.
• Pubmed ID:
  29708292
• Pubmed Central ID:
  PMC6207475
• Document Type:
  Journal Article
• Funding:
  P30 DK057516/DK/NIDDK NIH HHS/United States ; UC4 DK108173/DK/NIDDK NIH HHS/United States ; U01 DP000247/DP/NCCDPHP CDC HHS/United States ; U18 DP002710/DP/NCCDPHP CDC HHS/United States ; UL1 TR000154/TR/NCATS NIH HHS/United States ; U18 DP002714/DP/NCCDPHP CDC HHS/United States ; U01 DP000248/DP/NCCDPHP CDC HHS/United States ; U01 DP000244/DP/NCCDPHP CDC HHS/United States ; UL1 RR029882/RR/NCRR NIH HHS/United States ; U18 DP002709/DP/NCCDPHP CDC HHS/United States ; UL1 TR002319/TR/NCATS NIH HHS/United States ; UL1 TR000077/TR/NCATS NIH HHS/United States ; UL1 TR000423/TR/NCATS NIH HHS/United States ; U01 DP000250/DP/NCCDPHP CDC HHS/United States ; U01 DP000246/DP/NCCDPHP CDC HHS/United States ; U01 DP000254/DP/NCCDPHP CDC HHS/United States ; U18 DP002708/DP/NCCDPHP CDC HHS/United States ; HIR 10-001/HX/HSRD VA/United States
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:741411ecf5d878e4a5a27d8031ef9b5c6a05d2d085b9ae9e87b98e13611dfe01
• Download URL:
  https://stacks.cdc.gov/view/cdc/60198/cdc_60198_DS1.pdf
• File Type:
  [PDF - 324.03 KB ]