Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Gordon, Aubree ; Tsang, Tim K. ; Cowling, Benjamin J. ; Kuan, Guillermina ; Ojeda, Sergio ; ... More +
Gordon, Aubree ; Tsang, Tim K. ; Cowling, Benjamin J. ; Kuan, Guillermina ; Ojeda, Sergio ; Sanchez, Nery ; Gresh, Lionel ; Lopez, Roger ; Balmaseda, Angel ; Harris, Eva Less -
Description:
During August 2012-November 2014, we conducted a case ascertainment study to investigate household transmission of influenza virus in Managua, Nicaragua. We collected up to 5 respiratory swab samples from each of 536 household contacts of 133 influenza virus-infected persons and assessed for evidence of influenza virus transmission. The overall risk for influenza virus infection of household contacts was 15.7% (95% CI 12.7%-19.0%). Oseltamivir treatment of index patients did not appear to reduce household transmission. The mean serial interval for within-household transmission was 3.1 (95% CI 1.6-8.4) days. We found the transmissibility of influenza B virus to be higher than that of influenza A virus among children. Compared with households with <4 household contacts, those with >4 household contacts appeared to have a reduced risk for infection. Further research is needed to model household influenza virus transmission and design interventions for these settings.
Subjects:
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Adolescent Age Factors Child Child, Preschool Family Characteristics Female History, 21St Century Humans Infant Infant, Newborn Influenza, Human/Epidemiology Influenza, Human/History Influenza, Human/Transmission Influenza, Human/Virology Influenza A Virus Male Population Surveillance Socioeconomic Factors Urban Health
Source:
Emerg Infect Dis. 24(10):1882-1888.
Pubmed ID:
30226161
Pubmed Central ID:
PMC6154158
Document Type:
Journal Article
Genre:
Historical Article
Place as Subject:
Nicaragua
Location:
Central America
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:832c5a904d30a20cb8292626440236d8ee79500b519ddcae8ef60fd4cb0b6ec5
Download URL:
https://stacks.cdc.gov/view/cdc/59443/cdc_59443_DS1.pdf
File Type:

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