Correlation of Severity of Human Tick-Borne Encephalitis Virus Disease and Pathogenicity in Mice

Kurhade, Chaitanya; Schreier, Sarah; Lee, Yi-Ping; Zegenhagen, Loreen; Hjertqvist, Marika; Dobler, Gerhard; Kröger, Andrea; Överby, Anna K.

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Correlation of Severity of Human Tick-Borne Encephalitis Virus Disease and Pathogenicity in Mice

Sep 2018
By Kurhade, Chaitanya ; Schreier, Sarah ; Lee, Yi-Ping ; ...
Source: Emerg Infect Dis. 24(9):1709-1712.

[PDF-1.08 MB]

English

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Kurhade, Chaitanya ; Schreier, Sarah ; Lee, Yi-Ping ; Zegenhagen, Loreen ; Hjertqvist, Marika ; ... More +

Kurhade, Chaitanya ; Schreier, Sarah ; Lee, Yi-Ping ; Zegenhagen, Loreen ; Hjertqvist, Marika ; Dobler, Gerhard ; Kröger, Andrea ; Överby, Anna K. Less -
Description:

We compared 2 tick-borne encephalitis virus strains isolated from 2 different foci that cause different symptoms in tick-borne encephalitis patients, from neurologic to mild gastrointestinal symptoms. We compared neuroinvasiveness, neurovirulence, and proinflammatory cytokine response in mice and found unique differences that contribute to our understanding of pathogenesis.
Subjects:

[+]

Arboviral Diseases Correlation Of Severity Of Human Tick-Borne Encephalitis Virus Disease And Pathogenicity In Mice Dispatch Flavivirus Pathogenesis Tick-borne Encephalitis Tick-borne Encephalitis Virus Ticks Vector-borne Infections Viruses
Source:

Emerg Infect Dis. 24(9):1709-1712.
Pubmed ID:

30124404
Pubmed Central ID:

PMC6106420
Document Type:

Journal Article
Place as Subject:

Germany ; Sweden

Germany ; Sweden Less -
Location:

Europe
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:49af892ef68870fbeb91ffa82331d9e7ae7961da3c7bd29a7fa898d539dac6c1
Download URL:

https://stacks.cdc.gov/view/cdc/58640/cdc_58640_DS1.pdf
File Type:

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