Use of Favipiravir to Treat Lassa Virus Infection in Macaques

Rosenke, Kyle; Feldmann, Heinz; Westover, Jonna B.; Hanley, Patrick William; Martellaro, Cynthia; Feldmann, Friederike; Saturday, Greg; Lovaglio, Jamie; Scott, Dana P.; Furuta, Yousuke; Komeno, Takashi; Gowen, Brian B.; Safronetz, David

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CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners. As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.

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Use of Favipiravir to Treat Lassa Virus Infection in Macaques

Sep 17 2018
By Rosenke, Kyle ; Feldmann, Heinz ; Westover, Jonna B. ; ...
Source: Emerg Infect Dis. 24(9):1696-1699.

[PDF-2.14 MB]

English

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Rosenke, Kyle ; Feldmann, Heinz ; Westover, Jonna B. ; Hanley, Patrick William ; Martellaro, Cynthia ; ... More +

Rosenke, Kyle ; Feldmann, Heinz ; Westover, Jonna B. ; Hanley, Patrick William ; Martellaro, Cynthia ; Feldmann, Friederike ; Saturday, Greg ; Lovaglio, Jamie ; Scott, Dana P. ; Furuta, Yousuke ; Komeno, Takashi ; Gowen, Brian B. ; Safronetz, David Less -
Description:

Lassa virus, the cause of Lassa fever in humans, is endemic to West Africa. Treatment of Lassa fever is primarily supportive, although ribavirin has shown limited efficacy if administered early during infection. We tested favipiravir in Lassa virus-viremic macaques and found that 300 mg/kg daily for 2 weeks successfully treated infection.
Subjects:

[+]

Dispatch Use Of Favipiravir To Treat Lassa Virus Infection In Macaques
Source:

Emerg Infect Dis. 24(9):1696-1699.
Pubmed ID:

29882740
Pubmed Central ID:

PMC6106425
Document Type:

Journal Article
Volume:

24
Issue:

9
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:231a235f42a9857496c04a42a769a855226ef10f925e24ff7da48e62293f0e8c
Download URL:

https://stacks.cdc.gov/view/cdc/58628/cdc_58628_DS1.pdf
File Type:

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	18-0233-Techapp-s1.pdf	pdf
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