Abnormal Helminth Egg Development, Strange Morphology, and the Identification of Intestinal Helminth Infections

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Sapp, Sarah G.H. ; Yabsley, Michael J. ; Bradbury, Richard S.
• Description:
  Occasionally, abnormal forms of parasitic helminth eggs are detected during routine diagnostics. This finding can prove problematic in diagnosis because morphologic analysis based on tightly defined measurements is the primary method used to identify the infecting species and molecular confirmation of species is not always feasible. We describe instances of malformed nematode eggs (primarily from members of the superfamily Ascaridoidea) from human clinical practice and experimental trials on animals. On the basis of our observations and historical literature, we propose that unusual development and morphology of nematode and trematode eggs are associated with early infection. Further observational studies and experimentation are needed to identify additional factors that might cause abnormalities in egg morphology and production. Abnormal egg morphology can be observed early in the course of infection and can confound accurate diagnosis of intestinal helminthiases.
• Subjects:
  Animals Helminthiasis Humans Intestinal Diseases, Parasitic Nematoda Ovum Synopsis Trematoda
• Source:
  Emerg Infect Dis. 24(8):1407-1411
• Pubmed ID:
  30014830
• Pubmed Central ID:
  PMC6056116
• Document Type:
  Journal Article
• Volume:
  24
• Issue:
  8
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:2d129cdb86bd506f84015c77d37928cc292ca6bb16892b2bc71e0cc3c8fb8ac8
• Download URL:
  https://stacks.cdc.gov/view/cdc/57982/cdc_57982_DS1.pdf
• File Type:
  [PDF - 2.48 MB ]