Dapsone Resistance in Leprosy Patients Originally from American Samoa, United States, 2010–2012

Williams, Diana L.; Araujo, Sergio; Stryjewska, Barbara M.; Scollard, David

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Dapsone Resistance in Leprosy Patients Originally from American Samoa, United States, 2010–2012

Supporting Files Public Domain

August 2018
By Williams, Diana L. ; Araujo, Sergio ; Stryjewska, Barbara M. ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Williams, Diana L. ; Araujo, Sergio ; Stryjewska, Barbara M. ; Scollard, David
Description:

Skin biopsies from US leprosy patients were tested for mutations associated with drug resistance. Dapsone resistance was found in 4 of 6 biopsies from American Samoa patients. No resistance was observed in patients from other origins. The high rate of dapsone resistance in patients from American Samoa warrants further investigation.
Subjects:

Biopsy Clofazimine Dapsone Drug Administration Schedule Drug Resistance, Bacterial Genes, Bacterial Humans Leprostatic Agents Leprosy Microbial Sensitivity Tests Mutation Rifampin Skin
Source:

Emerg Infect Dis. 24(8):1584-1585
Pubmed ID:

30016255
Pubmed Central ID:

PMC6056125
Document Type:

Journal Article
Genre:

Letter
Place as Subject:

American Samoa
Volume:

24
Issue:

8
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:898b6c023f920b99b174c6f74a3b909112d9fc69120d63b56484a99dd08dbfd4
Download URL:

https://stacks.cdc.gov/view/cdc/57960/cdc_57960_DS1.pdf
File Type:

[PDF - 320.38 KB ]

18-0033.nxml

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File Language:

English

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