Case Definition of Chronic Pulmonary Aspergillosis in Resource-Constrained Settings

Denning, David W.; Page, Iain D.; Chakaya, Jeremiah; Jabeen, Kauser; Jude, Cecilia M.; Cornet, Muriel; Alastruey-Izquierdo, Ana; Bongomin, Felix; Bowyer, Paul; Chakrabarti, Arunaloke; Gago, Sara; Guto, John; Hochhegger, Bruno; Hoenigl, Martin; Irfan, Muhammad; Irurhe, Nicholas; Izumikawa, Koichi; Kirenga, Bruce; Manduku, Veronica; Moazam, Samihah; Oladele, Rita O.; Richardson, Malcolm D.; Tudela, Juan Luis Rodriguez; Rozaliyani, Anna; Salzer, Helmut J.F.; Sawyer, Richard; Simukulwa, Nasilele F.; Skrahina, Alena; Sriruttan, Charlotte; Setianingrum, Findra; Wilopo, Bayu A.P.; Cole, Donald C.; Getahun, Haileyesus

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Case Definition of Chronic Pulmonary Aspergillosis in Resource-Constrained Settings

Supporting Files Public Domain

August 2018
By Denning, David W. ; Page, Iain D. ; Chakaya, Jeremiah ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Denning, David W. ; Page, Iain D. ; Chakaya, Jeremiah ; Jabeen, Kauser ; Jude, Cecilia M. ; Cornet, Muriel ; Alastruey-Izquierdo, Ana ; Bongomin, Felix ; Bowyer, Paul ; Chakrabarti, Arunaloke ; Gago, Sara ; Guto, John ; Hochhegger, Bruno ; Hoenigl, Martin ; Irfan, Muhammad ; Irurhe, Nicholas ; Izumikawa, Koichi ; Kirenga, Bruce ; Manduku, Veronica ; Moazam, Samihah ; Oladele, Rita O. ; Richardson, Malcolm D. ; Tudela, Juan Luis Rodriguez ; Rozaliyani, Anna ; Salzer, Helmut J.F. ; Sawyer, Richard ; Simukulwa, Nasilele F. ; Skrahina, Alena ; Sriruttan, Charlotte ; Setianingrum, Findra ; Wilopo, Bayu A.P. ; Cole, Donald C. ; Getahun, Haileyesus
Description:

Chronic pulmonary aspergillosis (CPA) is a recognized complication of pulmonary tuberculosis (TB). In 2015, the World Health Organization reported 2.2 million new cases of nonbacteriologically confirmed pulmonary TB; some of these patients probably had undiagnosed CPA. In October 2016, the Global Action Fund for Fungal Infections convened an international expert panel to develop a case definition of CPA for resource-constrained settings. This panel defined CPA as illness for >3 months and all of the following: 1) weight loss, persistent cough, and/or hemoptysis; 2) chest images showing progressive cavitary infiltrates and/or a fungal ball and/or pericavitary fibrosis or infiltrates or pleural thickening; and 3) a positive Aspergillus IgG assay result or other evidence of Aspergillus infection. The proposed definition will facilitate advancements in research, practice, and policy in lower- and middle-income countries as well as in resource-constrained settings.
Subjects:

Chronic Disease Developing Countries Humans Online Report Practice Guidelines As Topic Pulmonary Aspergillosis Socioeconomic Factors
Source:

Emerg Infect Dis. 24(8)
Pubmed ID:

30016256
Pubmed Central ID:

PMC6056117
Document Type:

Journal Article
Volume:

24
Issue:

8
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:44e5817e8d57d5e6bb2f15ecd90d3e9570e4b70ffd138e8f48840e487a4f30fa
Download URL:

https://stacks.cdc.gov/view/cdc/57948/cdc_57948_DS1.pdf
File Type:

[PDF - 2.72 MB ]

File Language:

English

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