Welcome to CDC Stacks | HIV testing algorithms; a status report - 5696 | Stephen B. Thacker CDC Library collection
Stacks Logo
Advanced Search
Select up to three search categories and corresponding keywords using the fields to the right. Refer to the Help section for more detailed instructions.
 
 
Help
Clear All Simple Search
Advanced Search
HIV testing algorithms; a status report
Filetype[PDF - 504.55 KB]


Details:
  • Corporate Authors:
    Association of Public Health Laboratories (U.S.) ; Centers for Disease Control and Prevention (U.S.) ;
  • Description:
    Point-of-contact HIV testing algorithms - an overview -- Point-of-contact testing algorithm 1 - single rapid test for HIV screening -- Point-of-contact testing algorithm 2 - two rapid tests performed in sequence on blood -- Point-of-contact testing algorithm 3 - two rapid tests performed in sequence -- Point-of-contact testing algorithm 4 - three rapid HIV tests performed in sequence on blood -- Laboratory HIV testing algorithms - an overview -- Laboratory testing algorithm 1 - HIV-1 only immunoassay, with supplemental NAAT option -- Laboratory testing algorithm 2 - HIV-1/ HIV-2 immunoassay, with supplemental NAAT option -- Laboratory testing algorithm 3 - dual HIV-1/ HIV-2 immunoassay -- Laboratory testing algorithm 4 - acute HIV infection testing -- Laboratory testing algorithm 5 - HIV-2 testing -- Challenges and next steps

    HIV Testing Algorithms: A Status Report outlines a menu of testing algorithms, for both laboratory and point-of-contact laboratory settings based on the testing technology and data available in 2009. Since its publication, there have been several developments in the field of HIV diagnostics including the FDA-approval of antigen/antibody combination assays and the evaluation of new data. The Status Report was a great step forward in the process of updating the algorithm, and it remains an important source of historical information regarding the rationale for diagnostic strategies. The approval of antigen/antibody combination (fourth generation) immunoassay technology and the proceedings of the 2010 HIV Diagnostics Conference led to significant progress in the development of HIV testing strategies, and the release of updated recommendations for laboratory HIV testing superseded those in the Status Report.

    Date on cover: April 2009.

    Update: March 2010.

    Since HIV Testing Algorithms: A Status Report was published in April, 2009, several developments have occurred that necessitated an update to the report. At several points in the laboratory algorithms section of the report (pp. 25-31, 32, 39, 41), the April 2009 version stated that a plasma specimen is required to conduct HIV nucleic acid amplification testing (NAAT). The qualitative RNA NAAT that is FDAapproved as a supplemental test can now be used with serum specimens as well as plasma. Several instances in the Status Report (pp. 25, 29, 38, 39) also state that it may be necessary to repeat a positive NAAT for confirmation. This is only recommended with tests that are not FDA-approved for supplemental testing, or with specimens that are negative for HIV antibody.

  • Document Type:
  • Supporting Files:
    No Additional Files
No Related Documents.
You May Also Like: