Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Bougard, Daisy ; Bélondrade, Maxime ; Mayran, Charly ; Bruyère-Ostells, Lilian ; Lehmann, Sylvain ; ... More +
Bougard, Daisy ; Bélondrade, Maxime ; Mayran, Charly ; Bruyère-Ostells, Lilian ; Lehmann, Sylvain ; Fournier-Wirth, Chantal ; Knight, Richard S. ; Will, Robert G. ; Green, Alison J.E. Less -
Description:
A patient with a heterozygous variant of Creutzfeldt-Jakob disease (CJD) with a methionine/valine genotype at codon 129 of the prion protein gene was recently reported. Using an ultrasensitive and specific protein misfolding cyclic amplification-based assay for detecting variant CJD prions in cerebrospinal fluid, we discriminated this heterozygous case of variant CJD from cases of sporadic CJD.
Subjects:
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Cerebrospinal Fluid CJD Creutzfeldt-Jakob Disease CSF Diagnosis Diagnosis Of Methionine/Valine Variant Creutzfeldt-Jakob Disease By Protein Misfolding Cyclic Amplification Dispatch GCJD Genetic Creutzfeldt-Jakob Disease Methionine/valine Variant PMCA Prions And Related Diseases Protein Misfolding Cyclic Amplification SCJD Sporadic Creutzfeldt-Jakob Disease Variant Creutzfeldt-Jakob Disease VCJD
Source:
Emerg Infect Dis. 24(7):1364-1366.
Pubmed ID:
29912702
Pubmed Central ID:
PMC6038758
Document Type:
Journal Article
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:6950ab7ba23f8f4e8783f1cb2e87e550f5de804d8e6d729631a64d31aaeecaf8
Download URL:
https://stacks.cdc.gov/view/cdc/56947/cdc_56947_DS1.pdf
File Type:

Supporting Files

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