Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Bougard, Daisy; Bélondrade, Maxime; Mayran, Charly; Bruyère-Ostells, Lilian; Lehmann, Sylvain; ... More +
Bougard, Daisy; Bélondrade, Maxime; Mayran, Charly; Bruyère-Ostells, Lilian; Lehmann, Sylvain; Fournier-Wirth, Chantal; Knight, Richard S.; Will, Robert G.; Green, Alison J.E.; Less -
Description:
A patient with a heterozygous variant of Creutzfeldt-Jakob disease (CJD) with a methionine/valine genotype at codon 129 of the prion protein gene was recently reported. Using an ultrasensitive and specific protein misfolding cyclic amplification-based assay for detecting variant CJD prions in cerebrospinal fluid, we discriminated this heterozygous case of variant CJD from cases of sporadic CJD.
Subject:
[+]
Cerebrospinal Fluid
CJD
Creutzfeldt-Jakob Disease
CSF
Diagnosis
Diagnosis Of Methionine/Valine Variant Creutzfeldt-Jakob Disease By Protein Misfolding Cyclic Amplification
Dispatch
GCJD
Genetic Creutzfeldt-Jakob Disease
Methionine/valine Variant
PMCA
Prions And Related Diseases
Protein Misfolding Cyclic Amplification
SCJD
Sporadic Creutzfeldt-Jakob Disease
Variant Creutzfeldt-Jakob Disease
VCJD

Source:
Emerg Infect Dis. 24(7):1364-1366.;
Pubmed ID:
29912702
Pubmed Central ID:
PMC6038758
Document Type:
Journal Article;
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:6950ab7ba23f8f4e8783f1cb2e87e550f5de804d8e6d729631a64d31aaeecaf8
File Type:

Supporting Files

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