Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Bougard, Daisy ; Bélondrade, Maxime ; Mayran, Charly ; Bruyère-Ostells, Lilian ; Lehmann, Sylvain ; ... More +
Bougard, Daisy ; Bélondrade, Maxime ; Mayran, Charly ; Bruyère-Ostells, Lilian ; Lehmann, Sylvain ; Fournier-Wirth, Chantal ; Knight, Richard S. ; Will, Robert G. ; Green, Alison J.E. ; Less -
Description:
A patient with a heterozygous variant of Creutzfeldt-Jakob disease (CJD) with a methionine/valine genotype at codon 129 of the prion protein gene was recently reported. Using an ultrasensitive and specific protein misfolding cyclic amplification-based assay for detecting variant CJD prions in cerebrospinal fluid, we discriminated this heterozygous case of variant CJD from cases of sporadic CJD.
Subject:
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Cerebrospinal Fluid
CJD
Creutzfeldt-Jakob Disease
CSF
Diagnosis
Diagnosis Of Methionine/Valine Variant Creutzfeldt-Jakob Disease By Protein Misfolding Cyclic Amplification
Dispatch
GCJD
Genetic Creutzfeldt-Jakob Disease
Methionine/valine Variant
PMCA
Prions And Related Diseases
Protein Misfolding Cyclic Amplification
SCJD
Sporadic Creutzfeldt-Jakob Disease
Variant Creutzfeldt-Jakob Disease
VCJD

Source:
Emerg Infect Dis. 24(7):1364-1366. ;
Pubmed ID:
29912702
Pubmed Central ID:
PMC6038758
Document Type:
Journal Article ;
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:6950ab7ba23f8f4e8783f1cb2e87e550f5de804d8e6d729631a64d31aaeecaf8
File Type:

Supporting Files

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