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Diagnosis of Methionine/Valine Variant Creutzfeldt-Jakob Disease by Protein Misfolding Cyclic Amplification
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Jul 2018
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Source: Emerg Infect Dis. 24(7):1364-1366.
Details:
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Alternative Title:Emerg Infect Dis
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Personal Author:
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Description:A patient with a heterozygous variant of Creutzfeldt-Jakob disease (CJD) with a methionine/valine genotype at codon 129 of the prion protein gene was recently reported. Using an ultrasensitive and specific protein misfolding cyclic amplification-based assay for detecting variant CJD prions in cerebrospinal fluid, we discriminated this heterozygous case of variant CJD from cases of sporadic CJD.
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Subjects:
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Source:
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Pubmed ID:29912702
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Pubmed Central ID:PMC6038758
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Document Type:
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Volume:24
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Issue:7
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Main Document Checksum:
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Download URL:
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File Type:
[PDF-357.21 KB]
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