Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Demetria, Catalino ; Smith, Ina ; Tan, Titus ; Villarico, Daniel ; Simon, Edson Michael ; ... More +
Demetria, Catalino ; Smith, Ina ; Tan, Titus ; Villarico, Daniel ; Simon, Edson Michael ; Centeno, Rex ; Tachedjian, Mary ; Taniguchi, Satoshi ; Shimojima, Masayuki ; Miranda, Noel Lee J. ; Miranda, Mary Elizabeth ; Rondina, Melissa Marie R. ; Capistrano, Rowena ; Tandoc, Amado ; Marsh, Glenn ; Eagles, Debbie ; Cruz, Ramses ; Fukushi, Shuetsu Less -
Description:
In August 2015, a nonhuman primate facility south of Manila, the Philippines, noted unusual deaths of 6 cynomolgus monkeys (Macaca fascicularis), characterized by generalized rashes, inappetence, or sudden death. We identified Reston ebolavirus (RESTV) infection in monkeys by using serologic and molecular assays. We isolated viruses in tissues from infected monkeys and determined viral genome sequences. RESTV found in the 2015 outbreak is genetically closer to 1 of the 4 RESTVs that caused the 2008 outbreak among swine. Eight macaques, including 2 also infected with RESTV, tested positive for measles. Concurrently, the measles virus was circulating throughout the Philippines, indicating that the infection of the macaques may be a reverse zoonosis. Improved biosecurity measures will minimize the public health risk, as well as limit the introduction of disease and vectors.
Subjects:
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Animals Communicable Diseases, Emerging/epidemiology Communicable Diseases, Emerging/history Communicable Diseases, Emerging/virology Ebolavirus*classification Ebolavirus/genetics Genome, Viral Hemorrhagic Fever, Ebola/veterinary High-Throughput Nucleotide Sequencing History, 21st Century Humans Macaca Fascicularis/virology Monkey Diseases/epidemiology Monkey Diseases/history Monkey Diseases/virology Phylogeny Research
Source:
Emerg Infect Dis. 24(7):1285-1291.
Pubmed ID:
29912712
Pubmed Central ID:
PMC6038738
Document Type:
Journal Article
Place as Subject:
Philippines
Location:
Asia
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
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urn:sha256:7737a418b978c290ccfdffb1c68f7002ea7d76819abc0d610353f5b113df612f
Download URL:
https://stacks.cdc.gov/view/cdc/56927/cdc_56927_DS1.pdf
File Type:

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