Use of Urea Wash ELISA to Distinguish Zika and Dengue Virus Infections

Tsai, Wen-Yang; Youn, Han Ha; Tyson, Jasmine; Brites, Carlos; Tsai, Jih-Jin; Pedroso, Celia; Drexler, Jan Felix; Balmaseda, Angel; Harris, Eva; Wang, Wei-Kung

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Use of Urea Wash ELISA to Distinguish Zika and Dengue Virus Infections

Supporting Files Public Domain

Jul 2018
By Tsai, Wen-Yang ; Youn, Han Ha ; Tyson, Jasmine ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Tsai, Wen-Yang ; Youn, Han Ha ; Tyson, Jasmine ; Brites, Carlos ; Tsai, Jih-Jin ; Pedroso, Celia ; Drexler, Jan Felix ; Balmaseda, Angel ; Harris, Eva ; Wang, Wei-Kung
Description:

Serologic testing remains crucial for Zika virus diagnosis. We found that urea wash in a Zika virus nonstructural protein 1 IgG ELISA distinguishes secondary dengue virus infection from Zika virus infection with previous dengue (sensitivity 87.5%, specificity 93.8%). This test will aid serodiagnosis, serosurveillance, and monitoring of Zika complications in dengue-endemic regions.
Subjects:

Dengue Dengue Virus Dispatch Nonstructural Protein 1 Serologic Test Urea Viruses Zika Virus Zika Virus Infection
Source:

Emerg Infect Dis. 24(7):1355-1359.
Pubmed ID:

29912689
Pubmed Central ID:

PMC6038735
Document Type:

Journal Article
Volume:

24
Issue:

7
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:9c9bec7e6f54e7b53bac9d022ba3bef7588ef27fe0638378e3ceb17e233fdf9f
Download URL:

https://stacks.cdc.gov/view/cdc/56924/cdc_56924_DS1.pdf
File Type:

[PDF - 1013.79 KB ]

File Language:

English

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