Details:

Alternative Title:
MMWR Morb Mortal Wkly Rep
Personal Author:
Aliabadi, Negar ; Tate, Jacqueline E. ; Haynes, Amber K. ; Parashar, Umesh D.
Aliabadi, Negar ; Tate, Jacqueline E. ; Haynes, Amber K. ; Parashar, Umesh D. Less -
Description:
Rotavirus infection is the leading cause of severe gastroenteritis among infants and young children worldwide. Before the introduction of rotavirus vaccine in the United States in 2006, rotavirus infection caused significant morbidity among U.S. children, with an estimated 55,000-70,000 hospitalizations and 410,000 clinic visits annually. The disease showed a characteristic winter-spring seasonality and geographic pattern, with annual seasonal activity beginning in the West during December-January, extending across the country, and ending in the Northeast during April-May. To characterize changes in rotavirus disease trends and seasonality following introduction of rotavirus vaccines in the United States, CDC compared data from CDC's National Respiratory and Enteric Virus Surveillance System (NREVSS), a passive laboratory reporting system, for prevaccine (2000-2006) and postvaccine (2007-2014) years. National declines in rotavirus detection were noted, ranging from 57.8%-89.9% in each of the 7 postvaccine years compared with all 7 prevaccine years combined. A biennial pattern of rotavirus activity emerged in the postvaccine era, with years of low activity and highly erratic seasonality alternating with years of moderately increased activity and seasonality similar to that seen in the prevaccine era. These results demonstrate the substantial and sustained effect of rotavirus vaccine in reducing the circulation and changing the epidemiology of rotavirus among U.S. children.
Subject:
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Articles Child, Preschool Humans Infant Laboratories Population Surveillance Rotavirus Rotavirus Infections Rotavirus Vaccines Seasons Time Factors
Source:
MMWR Morb Mortal Wkly Rep. 2015; 64(13):337-342.
Pubmed ID:
25856253
Pubmed Central ID:
PMC4584623
Document Type:
Journal Article
Place as Subject:
United States
Collection(s):
Morbidity and Mortality Weekly Report (MMWR)
Main Document Checksum:
[+]
urn:sha256:13df4025eba374797495d9830db9f0a83350af36c6d48161419029d11aff66f0
Download URL:
https://stacks.cdc.gov/view/cdc/56816/cdc_56816_DS1.pdf
File Type:

Supporting Files

• 	337-342.nxml	xml
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