Hepatitis A Outbreak Among Adults with Developmental Disabilities in Group Homes — Michigan, 2013

Details

• Journal Article:
  Morbidity and Mortality Weekly Report (MMWR)
• Personal Author:
  Bohm, Susan R. ; Berger, Keira Wickliffe ; Hackert, Pamela B. ; Renas, Richard ; Brunette, Suzanne ; Parker, Nicole ; Padro, Carolyn ; Hocking, Anne ; Hedemark, Mary ; Edwards, Renai ; Bush, Russell L. ; Khudyakov, Yury ; Nelson, Noele P. ; Teshale, Eyasu H.
• Corporate Authors:
  National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (U.S.). Division of Viral Hepatitis.
• Description:
  Hepatitis A virus (HAV) infections among persons with developmental disabilities living in institutions were common in the past, but with improvements in care and fewer persons institutionalized, the number of HAV infections has declined in these institutions. However, residents in institutions are still vulnerable if they have not been vaccinated. On April 24, 2013, a resident of a group home (GH) for adults with disabilities in southeast Michigan (GH-A) was diagnosed with hepatitis A and died 2 days later of fulminant liver failure. Four weeks later, a second GH-A resident was diagnosed with hepatitis A. None of the GH-A residents or staff had been vaccinated against hepatitis A. Over the next 3 months, six more cases of hepatitis A were diagnosed in residents in four other Michigan GHs. Three local health departments were involved in case investigation and management, including administration of postexposure prophylaxis (PEP). Serum specimens from seven cases were found to have an identical strain of HAV genotype 1A. This report describes the outbreak investigation, the challenges of timely delivery of PEP for hepatitis A, and the need for preexposure vaccination against hepatitis A for adults living or working in GHs for the disabled.
• Subjects:
  Adult Causality Comorbidity Developmental Disabilities Disease Outbreaks Female Group Homes Hepatitis A Humans Male Middle Aged Post-Exposure Prophylaxis

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• Source:
  MMWR Morbidity Mortal Weekly Rep. 2015; 64(6):148-152.
• Series:
  Weekly Report: Morbidity and Mortality Weekly Report (MMWR)
• ISSN:
  0149-2195 (print) ; 1545-861X (digital)
• Pubmed ID:
  25695320
• Pubmed Central ID:
  PMC4584704
• Document Type:
  Journal Article
• Place as Subject:
  Michigan
• Pages in Document:
  5 pdf pages
• Volume:
  64
• Issue:
  6
• Collection(s):
  Morbidity and Mortality Weekly Report (MMWR)
• Main Document Checksum:
  urn:sha-512:f8fb8f04f85693ee66d5945c9a7a657d4f665ff81db2cc17b937e3645483c60fe0c507c5705b567ed2eaa93f2e3bc6e9451e69b645eafe92fac3602090073972
• Download URL:
  https://stacks.cdc.gov/view/cdc/55012/cdc_55012_DS1.pdf
• File Type:
  [PDF - 275.14 KB ]