Details:

Alternative Title:
MMWR Morb Mortal Wkly Rep
Personal Author:
Pastula, Daniel M. ; Aliabadi, Negar ; Haynes, Amber K. ; Messacar, Kevin ; Schreiner, Teri ; ... More +
Pastula, Daniel M. ; Aliabadi, Negar ; Haynes, Amber K. ; Messacar, Kevin ; Schreiner, Teri ; Maloney, John ; Dominguez, Samuel R. ; Davizon, Emily Spence ; Leshem, Eyal ; Fischer, Marc ; Nix, W. Allan ; Oberste, M. Steven ; Seward, Jane ; Feikin, Daniel ; Miller, Lisa Less -
Description:
On September 12, 2014, CDC was notified by the Colorado Department of Public Health and Environment of a cluster of nine children evaluated at Children's Hospital Colorado with acute neurologic illness characterized by extremity weakness, cranial nerve dysfunction (e.g., diplopia, facial droop, dysphagia, or dysarthria), or both. Neurologic illness onsets occurred during August 8-September 15, 2014. The median age of the children was 8 years (range = 1-18 years). Other than neck, back, or extremity pain in some patients, all had normal sensation. All had a preceding febrile illness, most with upper respiratory symptoms, occurring 3-16 days (median = 7 days) before onset of neurologic illness. Seven of eight patients with magnetic resonance imaging of the spinal cord had nonenhancing lesions of the gray matter of the spinal cord spanning multiple levels, and seven of nine with magnetic resonance imaging of the brain had nonenhancing brainstem lesions (most commonly the dorsal pons). Two of five with magnetic resonance imaging of the lumbosacral region had gadolinium enhancement of the ventral nerve roots of the cauda equina. Eight children were up to date on polio vaccination. Eight have not yet fully recovered neurologically.
Subject:
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Acute Disease
Adolescent
Articles
Child
Child, Preschool
Cluster Analysis
Humans
Infant
Nervous System Diseases

Source:
MMWR Morb Mortal Wkly Rep. 2014; 63(40):901-902.
Pubmed ID:
25299607
Pubmed Central ID:
PMC4584613
Document Type:
Journal Article
Place as Subject:
Colorado
Collection(s):
Morbidity and Mortality Weekly Report (MMWR)
Main Document Checksum:
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urn:sha256:58f541fa60a33854f23b96d0c5dce20b2bff0345477f9647da086aa8e3abb454
File Type:

Supporting Files

• 901-902.nxml

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