Follow-Up of Infants Diagnosed with HIV — Early Infant Diagnosis Program, Francistown, Botswana, 2005–2012

Details

• Journal Article:
  Morbidity and Mortality Weekly Report (MMWR)
• Personal Author:
  Motswere-Chirwa, Catherine ; Voetsch, Andrew ; Lu, Lydia ; Letsholathebe, Victor ; Lekone, Phenyo ; Machakaire, Esther ; Legwaila, Keitumetse ; Matambo, Stembile ; Maruping, Maruping ; Kolobe, Thatayotlhe ; Petlo, Chipo ; Lebelonyane, Refeletswe ; Glenshaw, Mary ; Dale, Helen ; Davis, Margarett ; El Halabi, Shenaaz ; Pelletier, Andrew
• Description:
  The 2011 prevalence of human immunodeficiency virus (HIV) among pregnant women in Botswana was 30.4%. High coverage rates of HIV testing and antiretroviral prophylaxis have reduced the rate of mother-to-child transmission of HIV in Botswana from as high as 40% with no prophylaxis to <4% in 2011. In June 2005, the national Early Infant Diagnosis (EID) Program began testing HIV-exposed infants (i.e., those born to HIV-infected mothers) for HIV using polymerase chain reaction (PCR) at 6 weeks postpartum. During 2005-2012, follow-up of all HIV-infected infants diagnosed in all 13 postnatal care facilities in Francistown, Botswana, was conducted to ascertain patient outcomes. A total of 202 infants were diagnosed with HIV. As of September 2013, 82 (41%) children were alive and on antiretroviral therapy (ART), 79 (39%) had died, and 41 (20%) were either lost to follow-up, had transferred, or their mothers declined ART. Despite success in preventing mother-to-child transmission in Botswana, results of the EID program highlight the need for early diagnosis of HIV-infected infants, prompt initiation of ART, and retention in care.
• Subjects:
  Anti-HIV Agents Counseling Female Follow-Up Studies HIV Infections Humans Infant Infectious Disease Transmission, Vertical Male Polymerase Chain Reaction Pregnancy Pregnancy Complications, Infectious Program Evaluation Survival Rate Treatment Outcome

  More +
• Source:
  MMWR Morbidity Mortal Weekly Rep. 2014; 63(7):158-160.
• Series:
  Weekly Report: Morbidity and Mortality Weekly Report (MMWR)
• ISSN:
  0149-2195 (print) ; 1545-861X (digital)
• Pubmed ID:
  24553200
• Pubmed Central ID:
  PMC4584761
• Document Type:
  Journal Article
• Place as Subject:
  Botswana
• Pages in Document:
  3 pdf pages
• Volume:
  63
• Issue:
  7
• Collection(s):
  Morbidity and Mortality Weekly Report (MMWR)
• Main Document Checksum:
  urn:sha-512:4b143c58af2a6121effcd521008859e24f3e7346ba94cde63cc9f111e5584570b9faff466e20cb138e272cfbae435dd7b9b930a3bd78c76bf28b55c91b10bfa3
• Download URL:
  https://stacks.cdc.gov/view/cdc/54815/cdc_54815_DS1.pdf
• File Type:
  [PDF - 178.79 KB ]