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Investigation of a Cluster of Neural Tube Defects — Central Washington, 2010–2013

Supporting Files Public Domain


Details

  • Journal Article:
    Morbidity and Mortality Weekly Report (MMWR)
  • Description:
    During August 2012, a health-care provider in central Washington alerted the Washington State Department of Health (DOH) about an excessive number of anencephaly births at a local hospital. After examining referral patterns for high-risk pregnancies in central Washington, DOH identified pregnancies affected by a severe neural tube defect (NTD) in a three-county area. Case findings included a review of area hospital discharge records for International Classification of Diseases, Ninth Revision codes 740, 741, 742, or 655.0; vital statistics reports; and perinatology office records. From these sources, 27 confirmed NTD-affected pregnancies occurring during January 2010-January 2013 were identified among women residing in the three-county area. Twenty-three pregnancies were affected by anencephaly, three with spina bifida, and one with encephalocele. The anencephaly rate was 8.4 per 10,000 live births (95% confidence interval [CI] = 4.5-12.0), compared with a national estimate of 2.1 per 10,000 live births (CI = 1.9-2.2). In contrast, the rate of spina bifida was 1.3 per 10,000 live births (CI = 0.3-3.8), compared with 3.5 per 10,000 live births nationally (CI = 3.3-3.7).
  • Subjects:
  • Source:
    MMWR Morbidity Mortal Weekly Rep. 2013; 62(35):728.
  • Series:
    Weekly Report: Morbidity and Mortality Weekly Report (MMWR)
  • ISSN:
    0149-2195 (print) ; 1545-861X (digital)
  • Pubmed ID:
    24005228
  • Pubmed Central ID:
    PMC4585626
  • Document Type:
    Journal Article
  • Place as Subject:
    Washington
  • Pages in Document:
    1 pdf page
  • Volume:
    62
  • Issue:
    35
  • Collection(s):
  • Main Document Checksum:
    urn:sha-512:f55c363cd020da7871898bbb55911d3f01df4e1d8f0ffb572e8788a32c29cc135b857759a3734d8d7de37fdc96d0cb163a81a4aaed1572b567e130bd6b60dae0
  • Download URL:
  • File Type:
    Filetype[PDF - 90.48 KB ]

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