Investigational Drug Available Directly from CDC for the Treatment of Infections with Free-Living Amebae

Details

• Journal Article:
  Morbidity and Mortality Weekly Report (MMWR)
• Personal Author:
  Cope, Jennifer R.
• Description:
  Infections caused by free-living amebae (FLA) are severe and life-threatening. These infections include primary amebic meningoencephalitis (PAM) caused by Naegleria fowleri and granulomatous amebic encephalitis caused by Balamuthia mandrillaris and Acanthamoeba species. Although several drugs have in vitro activity against FLA, Mortality from these infections remains>90% despite treatment with combinations of drugs.
• Subjects:
  Acanthamoeba Amebiasis Animals Antiprotozoal Agents Articles Balamuthia Mandrillaris Central Nervous System Protozoal Infections Drugs, Investigational Encephalitis Humans Naegleria Fowleri Phosphorylcholine Treatment Outcome

  More +
• Source:
  MMWR Morbidity Mortal Weekly Rep. 2013; 62(33):666.
• Series:
  Weekly Report: Morbidity and Mortality Weekly Report (MMWR)
• ISSN:
  0149-2195 (print) ; 1545-861X (digital)
• Pubmed ID:
  23965830
• Pubmed Central ID:
  PMC4604798
• Document Type:
  Journal Article
• Place as Subject:
  United States
• Pages in Document:
  1 pdf page
• Volume:
  62
• Issue:
  33
• Collection(s):
  Morbidity and Mortality Weekly Report (MMWR)
• Main Document Checksum:
  urn:sha-512:0aa0fbe387dd7c49a9bd2d554e3edbcd34f53341b998fc5790c515835d6297eb405cae50bb7fa2f345235f2e7e6a0d9b5f04f1f3b8eea6fee0b6e2221d5566db
• Download URL:
  https://stacks.cdc.gov/view/cdc/54687/cdc_54687_DS1.pdf
• File Type:
  [PDF - 95.16 KB ]