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The disconnect between a national tuberculosis drug resistance survey and treatment outcomes: a lost opportunity
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11 2014
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Source: Int J Tuberc Lung Dis. 18(11):1319-1322
[PDF-239.87 KB]
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Alternative Title:Int J Tuberc Lung Dis
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Description:We linked results from the Fourth Botswana National Drug Resistance Survey (DRS), 2007-2008, to patient records from the national Electronic Tuberculosis Registry to determine treatment outcomes. Of 915 new patients, 651 (71%) had treatment data available. Completion or cure was achieved for 10/15 (67%, 95%CI 42-85) with isoniazid monoresistance, (6/16, 38%, 95%CI 18-61) with multidrug resistance, while 73% (391/537, 95%CI 69-76) were susceptible to first-line drugs. The analysis was limited because of unavailable treatment records and undocumented outcomes. Prospective analyses following DRSs should be considered to ensure adequate outcome data.
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Pubmed ID:25299864
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Pubmed Central ID:PMC5931357
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Volume:18
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Issue:11
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