Details:

Alternative Title:
Investig Clin Urol
Publisher's site:
http://dx.doi.org/10.4111/icu.2018.59.2.72
Personal Author:
Piao, Xuan-Mei ; Byun, Young Joon ; Kim, Wun-Jae ; Kim, Jayoung
Piao, Xuan-Mei ; Byun, Young Joon ; Kim, Wun-Jae ; Kim, Jayoung Less -
Description:
Precision medicine is designed to tailor treatments for individual patients by factoring in each person's specific biology and mechanism of disease. This paradigm shifted from a "one size fits all" approach to "personalized and precision care" requires multiple layers of molecular profiling of biomarkers for accurate diagnosis and prediction of treatment responses. Intensive studies are also being performed to understand the complex and dynamic molecular profiles of bladder cancer. These efforts involve looking bladder cancer mechanism at the multiple levels of the genome, epigenome, transcriptome, proteome, lipidome, metabolome etc. The aim of this short review is to outline the current technologies being used to investigate molecular profiles and discuss biomarker candidates that have been investigated as possible diagnostic and prognostic indicators of bladder cancer.
Subjects:
[+]
Biomarkers Liquid Biopsy Precision Medicine Review Article Urinary Bladder Neoplasms
Source:
Investig Clin Urol. 2018; 59(2):72-82.
Pubmed ID:
29520382
Pubmed Central ID:
PMC5840121
Document Type:
Journal Article
Funding:
U01 DK103260/DK/NIDDK NIH HHS/United States ; U01 DP006079/DP/NCCDPHP CDC HHS/United States
U01 DK103260/DK/NIDDK NIH HHS/United States ; U01 DP006079/DP/NCCDPHP CDC HHS/United States Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:27159a56c2dddfb01e227a13e016ce8591e473c86b6abc7aac25ecd18c587c65
Download URL:
https://stacks.cdc.gov/view/cdc/53655/cdc_53655_DS1.pdf
File Type:

Supporting Files

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  	icu-59-72-g001.jpg	jpeg
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