The Preexposure Prophylaxis for the Prevention of HIV Infection in the United States – 2014 was published in an electronic format in July 2014 so that it could be updated as relevant changes in supporting evidence became available. The Preexposure Prophylaxis forthe Prevention of HIV Infection in the United States – 2016: Update – A Clinical Practice Guideline includes revisions to several sections. These revisions are highlighted throughout the document and are intended solely to update the developing evidence base or to clarify specific points in clinical care. No changes were made to the graded recommendations for the use of PrEP in the US.

Priya Jakhmola (CPY5@cdc.gov) 4/20/2018

Guidelines and Recommendations