Carbapenem-Nonsusceptible Acinetobacter baumannii, 8 US Metropolitan Areas, 2012–2015

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Bulens, Sandra N. ; Yi, Sarah H. ; Walters, Maroya S. ; Jacob, Jesse T. ; Bower, Chris ; Reno, Jessica ; Wilson, Lucy ; Vaeth, Elisabeth ; Bamberg, Wendy ; Janelle, Sarah J. ; Lynfield, Ruth ; Vagnone, Paula Snippes ; Shaw, Kristin ; Kainer, Marion ; Muleta, Daniel ; Mounsey, Jacqueline ; Dumyati, Ghinwa ; Concannon, Cathleen ; Beldavs, Zintars ; Cassidy, P. Maureen ; Phipps, Erin C. ; Kenslow, Nicole ; Hancock, Emily B. ; Kallen, Alexander J.
• Description:
  In healthcare settings, Acinetobacter spp. bacteria commonly demonstrate antimicrobial resistance, making them a major treatment challenge. Nearly half of Acinetobacter organisms from clinical cultures in the United States are nonsusceptible to carbapenem antimicrobial drugs. During 2012-2015, we conducted laboratory- and population-based surveillance in selected metropolitan areas in Colorado, Georgia, Maryland, Minnesota, New Mexico, New York, Oregon, and Tennessee to determine the incidence of carbapenem-nonsusceptible A. baumannii cultured from urine or normally sterile sites and to describe the demographic and clinical characteristics of patients and cases. We identified 621 cases in 537 patients; crude annual incidence was 1.2 cases/100,000 persons. Among 598 cases for which complete data were available, 528 (88.3%) occurred among patients with exposure to a healthcare facility during the preceding year; 506 (84.6%) patients had an indwelling device. Although incidence was lower than for other healthcare-associated pathogens, cases were associated with substantial illness and death.
• Subjects:
  Acinetobacter Baumannii/drug Effects Acinetobacter Infections/epidemiology Acinetobacter Infections/history Acinetobacter Infections/microbiology Adolescent Adult Aged Aged, 80 And Over Carbapenems/pharmacology Child Child, Preschool Drug Resistance, Bacterial Female History, 21st Century Humans Incidence Infant Infant, Newborn Male Middle Aged Population Surveillance Research Young Adult

  More +
• Source:
  Emerg Infect Dis. 24(4):727-734.
• Pubmed ID:
  29553339
• Pubmed Central ID:
  PMC5875254
• Document Type:
  Journal Article
• Place as Subject:
  United States
• Location:
  North America
• Volume:
  24
• Issue:
  4
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:8725cd531c07c1b2ff59854c8e057987d28c5e693ece043e2bb0355aa4c88bf4
• Download URL:
  https://stacks.cdc.gov/view/cdc/53060/cdc_53060_DS1.pdf
• File Type:
  [PDF - 670.43 KB ]