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Imipenem Resistance in Clostridium difficile Ribotype 017, Portugal
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Apr 2018
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Source: Emerg Infect Dis. 24(4):741-745.
[PDF-1.98 MB]
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Alternative Title:Emerg Infect Dis
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Description:We describe imipenem-resistant and imipenem-susceptible clinical isolates of Clostridium difficile ribotype 017 in Portugal. All ribotype 017 isolates carried an extra penicillin-binding protein gene, pbp5, and the imipenem-resistant isolates had additional substitutions near the transpeptidase active sites of pbp1 and pbp3. These clones could disseminate and contribute to imipenem resistance.
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Pubmed ID:29553322
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Pubmed Central ID:PMC5875251
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Document Type:
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Volume:24
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Issue:4
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