Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Isidro, Joana ; Santos, Andrea ; Nunes, Alexandra ; Borges, Vítor ; Silva, Catarina ; ... More +
Isidro, Joana ; Santos, Andrea ; Nunes, Alexandra ; Borges, Vítor ; Silva, Catarina ; Vieira, Luís ; Mendes, Aristides L. ; Serrano, Mónica ; Henriques, Adriano O. ; Gomes, João Paulo ; Oleastro, Mónica Less -
Description:
We describe imipenem-resistant and imipenem-susceptible clinical isolates of Clostridium difficile ribotype 017 in Portugal. All ribotype 017 isolates carried an extra penicillin-binding protein gene, pbp5, and the imipenem-resistant isolates had additional substitutions near the transpeptidase active sites of pbp1 and pbp3. These clones could disseminate and contribute to imipenem resistance.
Subject:
[+]
Antimicrobial Resistance
Bacteria
CDI
Clostridium Difficile
Clostridium Difficile Infection
Dispatch
Imipenem Resistance
Imipenem Resistance In Clostridium Difficile Ribotype 017, Portugal
Multidrug Resistance
Penicillin-binding Proteins
Portugal
Ribotype 017

Source:
Emerg Infect Dis. 24(4):741-745.
Pubmed ID:
29553322
Pubmed Central ID:
PMC5875251
Document Type:
Journal Article
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
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urn:sha256:81f2e4c58fb5bcb933625bb098eb8c775b59978661255b7d02fabcb48e990d5c
File Type:

Supporting Files

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  	17-0095-Techapp-s1.pdf	pdf
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