Contraception

Objective The objective was to assess the extent of concordance between self-reported contraceptive use and the presence of contraceptive progestins in serum. Study design We evaluated self-reported contraceptive use by using radioimmunoassay to examine baseline serum levels of medroxyprogesterone acetate (MPA) and levonorgestrel (LNG) among 97 Malawian women enrolling in a contraceptive trial. Results Twelve percent (12/97) of study participants who reported no hormonal contraceptive use in the previous 6 months had either MPA or LNG detected in their serum. Conclusions The observed discordance between self-report and detection of exogenous hormones in serum indicates that caution is warranted when drawing conclusions based on self-reported contraceptive use.

29246819

PMC5840008

Journal Article

CDC Public Access