Discordance between self-reported contraceptive use and detection of exogenous hormones among Malawian women enrolling in a randomized clinical trial☆

Nwaohiri, Anuli N.; Tang, Jennifer H.; Stanczyk, Frank; Chinula, Lameck; Hurst, Stacey; Davis, Nicole L.; Tegha, Gerald; Haddad, Lisa; Kourtis, Athena P.

doi:10.1016/j.contraception.2017.12.007

- Add this to...
- Twitter
- Facebook
- Google Bookmarks
- LinkedIn

Discordance between self-reported contraceptive use and detection of exogenous hormones among Malawian women enrolling in a randomized clinical trial☆

Published Date:

December 13 2017

Publisher's site:

http://dx.doi.org/10.1016/j.contraception.2017.12.007 New Site Icon

Source:

Contraception. 97(4):354-356

Language:

English

[PDF-295.55 KB]

Details:

Personal Authors:

Nwaohiri, Anuli N. ; Tang, Jennifer H. ; Stanczyk, Frank ; Chinula, Lameck ; Hurst, Stacey ; ... More ▼

Keywords:

[+]

Pubmed ID:

29246819

Pubmed Central ID:

PMC5840008

Description:

Objective

The objective was to assess the extent of concordance between self-reported contraceptive use and the presence of contraceptive progestins in serum.

Study design

We evaluated self-reported contraceptive use by using radioimmunoassay to examine baseline serum levels of medroxyprogesterone acetate (MPA) and levonorgestrel (LNG) among 97 Malawian women enrolling in a contraceptive trial.

Results

Twelve percent (12/97) of study participants who reported no hormonal contraceptive use in the previous 6 months had either MPA or LNG detected in their serum.

Conclusions

The observed discordance between self-report and detection of exogenous hormones in serum indicates that caution is warranted when drawing conclusions based on self-reported contraceptive use.

Document Type:

Journal Article

Collection(s):

CDC Public Access

Funding:

K01 TW009657/TW/FIC NIH HHS/United States
K23 HD078153/HD/NICHD NIH HHS/United States
P30 AI050410/AI/NIAID NIH HHS/United States
U48 DP001944/DP/NCCDPHP CDC HHS/United States

Main Document Checksum:

[+]

Supporting Files:

nihms934669.nxml

text/xml

No Related Documents.

You May Also Like:

Effect of the depot medroxyprogesterone acetate injectable and levonorgestrel implant on HIV genital shedding: a randomized trial☆☆☆★★★

Personal Author:

Chinula, Lameck; Nelson, Julie A.E.; Wiener, Jeffrey; Tang, Jennifer H.; Hurst, Stacey; Tegha, Gerald; Msika, Albans; Ellington, Sascha; Hosseinipour, Mina C.; Mataya, Ronald; Haddad, Lisa B.; Kourtis, Athena P.;

Published:

May 08 2018

Source:

Contraception. 2018; 98(3):193-198.

Description:

Objectives : To assess the effect of the depot medroxyprogesterone acetate injectable (DMPA) and of the levonorgestrel (LNG) implant on genital HIV shedding among women receiving antiretroviral therapy (ART). : Methods : We randomized HIV-infected Ma...

File Type:

[PDF - 815.69 KB]
HIV shedding in the female genital tract of women on ART and progestin contraception: Extended follow-up results of a randomized clinical trial

Personal Author:

Kourtis, Athena P.; Wiener, Jeffrey; Hurst, Stacey; Nelson, Julie A.E.; Cottrell, Mackenzie L.; Corbett, Amanda; Chinula, Lameck; Msika, Albans; Haddad, Lisa B.; Tang, Jennifer H.;

Published:

Jun 01 2019

Source:

J Acquir Immune Defic Syndr. 81(2):163-165

Description:

Background: : Progestin contraception has been linked to higher risk of female to male sexual HIV transmission. : Setting: : A clinical trial among HIV-infected women in Lilongwe, Malawi, randomized to initiation of depomedroxyprogesterone acetate (D...

Public Access
Available on:

June 01, 2020
Do Women Using Long-Acting Reversible Contraception Reduce Condom Use? A Novel Study Design Incorporating Semen Biomarkers

Personal Author:

Gallo, Maria F.; Warner, Lee; Jamieson, Denise J.; Steiner, Markus J.;

Published:

Aug 07 2011

Source:

Infect Dis Obstet Gynecol. 2011; 2011.

Description:

Long-acting reversible contraceptive (LARC) methods are highly effective against pregnancy. A barrier to their widespread promotion can include the concern they will lead reduced condom use and, thus, will put couples at higher risk for sexually tran...

File Type:

[PDF - 490.50 KB]
Simultaneous quantitation of multiple contraceptive hormones in human serum by LC-MS/MS

Personal Author:

Blue, Steven W.; Winchell, Andrea J.; Kaucher, Amy V.; Lieberman, Rachel A.; Gilles, Christopher T.; Pyra, Maria N.; Heffron, Renee; Hou, Xuanlin; Coombs, Robert W.; Nanda, Kavita; Davis, Nicole L.; Kourtis, Athena P.; Herbeck, Joshua T.; Baeten, Jared M.; Lingappa, Jairam R.; Erikson, David W.;

Published:

Jan 31 2018

Source:

Contraception. 97(4):363-369.

Description:

Objective : To develop a method to simultaneously quantify five commonly used hormonal contraceptives (HC) and 2 endogenous sex steroids by liquid chromatography-tandem triple quadrupole mass spectrometry (LC-MS/MS) and apply this method to human ser...

File Type:

[PDF - 1.04 MB]
Reproductive factors and risk of lung cancer in female textile workers in Shanghai, China

Personal Author:

Gallagher, Lisa G.; Rosenblatt, Karin A.; Ray, Roberta M.; Li, Wenjin; Gao, Dao L.; Applebaum, Katie M.; Checkoway, Harvey; Thomas, David B.;

Published:

Apr 13 2013

Source:

Cancer Causes Control. 24(7):1305-1314.

Description:

Purpose : Hormonal factors may play a role in the development of lung cancer in women. This study examined the relationship between lung cancer and reproductive factors in a large cohort of women, most of whom never smoked (97%). : Methods : A cohort...

File Type:

[PDF - 293.96 KB]