Discordance between self-reported contraceptive use and detection of exogenous hormones among Malawian women enrolling in a randomized clinical trial☆

Nwaohiri, Anuli N.; Tang, Jennifer H.; Stanczyk, Frank; Chinula, Lameck; Hurst, Stacey; Davis, Nicole L.; Tegha, Gerald; Haddad, Lisa; Kourtis, Athena P.

doi:10.1016/j.contraception.2017.12.007

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Discordance between self-reported contraceptive use and detection of exogenous hormones among Malawian women enrolling in a randomized clinical trial☆

Published Date:

December 13 2017

Publisher's site:

http://dx.doi.org/10.1016/j.contraception.2017.12.007 New Site Icon

Source:

Contraception. 97(4):354-356

Language:

English

[PDF-295.55 KB]

Details:

Alternative Title:

Contraception

Personal Author:

Nwaohiri, Anuli N. ; Tang, Jennifer H. ; Stanczyk, Frank ; Chinula, Lameck ; Hurst, Stacey ; ... More ▼

Description:

Objective

The objective was to assess the extent of concordance between self-reported contraceptive use and the presence of contraceptive progestins in serum.

Study design

We evaluated self-reported contraceptive use by using radioimmunoassay to examine baseline serum levels of medroxyprogesterone acetate (MPA) and levonorgestrel (LNG) among 97 Malawian women enrolling in a contraceptive trial.

Results

Twelve percent (12/97) of study participants who reported no hormonal contraceptive use in the previous 6 months had either MPA or LNG detected in their serum.

Conclusions

The observed discordance between self-report and detection of exogenous hormones in serum indicates that caution is warranted when drawing conclusions based on self-reported contraceptive use.

Subject:

[+]

Pubmed ID:

29246819

Pubmed Central ID:

PMC5840008

Document Type:

Journal Article

Funding:

K01 TW009657/TW/FIC NIH HHS/United States ; K23 HD078153/HD/NICHD NIH HHS/United States ; P30 AI050410/AI/NIAID NIH HHS/United States ; U48 DP001944/DP/NCCDPHP CDC HHS/United States ;

Collection(s):

CDC Public Access

Main Document Checksum:

[+]

Supporting Files:

nihms934669.nxml

text/xml

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