Discordance between self-reported contraceptive use and detection of exogenous hormones among Malawian women enrolling in a randomized clinical trial☆

Details

• Alternative Title:
  Contraception
• Personal Author:
  Nwaohiri, Anuli N. ; Tang, Jennifer H. ; Stanczyk, Frank ; Chinula, Lameck ; Hurst, Stacey ; Davis, Nicole L. ; Tegha, Gerald ; Haddad, Lisa ; Kourtis, Athena P.
• Description:
  Objective
  
  The objective was to assess the extent of concordance between self-reported contraceptive use and the presence of contraceptive progestins in serum.
  
  Study design
  
  We evaluated self-reported contraceptive use by using radioimmunoassay to examine baseline serum levels of medroxyprogesterone acetate (MPA) and levonorgestrel (LNG) among 97 Malawian women enrolling in a contraceptive trial.
  
  Results
  
  Twelve percent (12/97) of study participants who reported no hormonal contraceptive use in the previous 6 months had either MPA or LNG detected in their serum.
  
  Conclusions
  
  The observed discordance between self-report and detection of exogenous hormones in serum indicates that caution is warranted when drawing conclusions based on self-reported contraceptive use.
  
  
• Subjects:
  Adult Contraception Behavior Contraceptive Agents, Female Female Humans Levonorgestrel Malawi Medroxyprogesterone Acetate Radioimmunoassay Self Report Truth Disclosure

  More +
• Keywords:
  Contraceptive Use Discordance Levonorgestrel (LNG) Medroxyprogesterone Acetate (MPA) Misreporting
• Source:
  Contraception. 97(4):354-356
• Pubmed ID:
  29246819
• Pubmed Central ID:
  PMC5840008
• Document Type:
  Journal Article
• Funding:
  U48 DP001944/DP/NCCDPHP CDC HHSUnited States/ ; P30 AI050409/AI/NIAID NIH HHSUnited States/ ; U48DP001944/ACL/ACL HHSUnited States/ ; K01 TW009657/TW/FIC NIH HHSUnited States/ ; K23 HD078153/HD/NICHD NIH HHSUnited States/ ; P30 AI050410/AI/NIAID NIH HHSUnited States/
• Volume:
  97
• Issue:
  4
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:b79b2416205f03c4b48e1065f7ff4f93f14275f1fc386d880945016b33dd61b4
• Download URL:
  https://stacks.cdc.gov/view/cdc/52388/cdc_52388_DS1.pdf
• File Type:
  [PDF - 295.55 KB ]