Epidemiology of Recurrent Hand, Foot and Mouth Disease, China, 2008–2015

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Huang, Jiao ; Liao, Qiaohong ; Ooi, Mong How ; Cowling, Benjamin J. ; Chang, Zhaorui ; Wu, Peng ; Liu, Fengfeng ; Li, Yu ; Luo, Li ; Yu, Shuanbao ; Yu, Hongjie ; Wei, Sheng
• Description:
  Using China's national surveillance data on hand, foot and mouth disease (HFMD) for 2008-2015, we described the epidemiologic and virologic features of recurrent HFMD. A total of 398,010 patients had HFMD recurrence; 1,767 patients had 1,814 cases of recurrent laboratory-confirmed HFMD: 99 reinfections of enterovirus A71 (EV-A71) with EV-A71, 45 of coxsackievirus A16 (CV-A16) with CV-A16, 364 of other enteroviruses with other enteroviruses, 383 of EV-A71 with CV-A16 and CV-A16 with EV-A71, and 923 of EV-A71 or CV-A16 with other enteroviruses and other enteroviruses with EV-A71 or CV-A16. The probability of HFMD recurrence was 1.9% at 12 months, 3.3% at 24 months, 3.9% at 36 months, and 4.0% at 38.8 months after the primary episode. HFMD severity was not associated with recurrent episodes or time interval between episodes. Elucidation of the mechanism underlying HFMD recurrence with the same enterovirus serotype and confirmation that HFMD recurrence is not associated with disease severity is needed.
• Subjects:
  Adolescent Child Child, Preschool Enterovirus/classification Epidemics Female Geography, Medical Hand, Foot And Mouth Disease/epidemiology Hand, Foot And Mouth Disease/history Hand, Foot And Mouth Disease/virology History, 21st Century Humans Infant Kaplan-Meier Estimate Male Probability Public Health Surveillance Recurrence Severity Of Illness Index Synopsis

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• Source:
  Emerg Infect Dis. 24(3):432-442.
• Pubmed ID:
  29460747
• Pubmed Central ID:
  PMC5823341
• Document Type:
  Journal Article
• Place as Subject:
  China
• Location:
  Asia
• Volume:
  24
• Issue:
  3
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:241a22afdaff03752294de7087c16a3365ae2f2f88c0d8ba693f4d08ee7ac31d
• Download URL:
  https://stacks.cdc.gov/view/cdc/52190/cdc_52190_DS1.pdf
• File Type:
  [PDF - 3.00 MB ]